Etiology and pathogenesis of multiple sclerosis

Torben Lykke Sørensen; R M Ransohoff

doi:10.1055/s-2008-1040879

Etiology and pathogenesis of multiple sclerosis

Torben Lykke Sørensen, R M Ransohoff

Institut for Klinisk Medicin

44 Citationer (Scopus)

Abstract

The cause of multiple sclerosis (MS) remains unknown despite decades of intense research. The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology. Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.

Originalsprog	Engelsk
Tidsskrift	Seminars in Neurology
Vol/bind	18
Udgave nummer	3
Sider (fra-til)	287-94
Antal sider	8
ISSN	0271-8235
DOI	https://doi.org/10.1055/s-2008-1040879
Status	Udgivet - 1998

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10.1055/s-2008-1040879

Citationsformater

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title = "Etiology and pathogenesis of multiple sclerosis",

abstract = "The cause of multiple sclerosis (MS) remains unknown despite decades of intense research. The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology. Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.",

keywords = "Autoimmune Diseases, Genetic Predisposition to Disease, Humans, Inflammation, Lymphocyte Activation, Multiple Sclerosis, T-Lymphocytes",

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AU - Sørensen, Torben Lykke

AU - Ransohoff, R M

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N2 - The cause of multiple sclerosis (MS) remains unknown despite decades of intense research. The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology. Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.

AB - The cause of multiple sclerosis (MS) remains unknown despite decades of intense research. The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology. Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.

KW - Autoimmune Diseases

KW - Genetic Predisposition to Disease

KW - Humans

KW - Inflammation

KW - Lymphocyte Activation

KW - Multiple Sclerosis

KW - T-Lymphocytes

U2 - 10.1055/s-2008-1040879

DO - 10.1055/s-2008-1040879

M3 - Journal article

C2 - 9817532

SN - 0271-8235

VL - 18

SP - 287

EP - 294

JO - Seminars in Neurology

JF - Seminars in Neurology

IS - 3

ER -

Etiology and pathogenesis of multiple sclerosis

Abstract

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