TY - JOUR
T1 - Estimating the probability of allelic drop-out of STR alleles in forensic genetics
AU - Tvedebrink, Torben
AU - Eriksen, Poul Svante
AU - Mogensen, Helle Smidt
AU - Morling, Niels
PY - 2009
Y1 - 2009
N2 - In crime cases with available DNA evidence, the amount of DNA is often sparse due to the setting of the crime. In such cases, allelic drop-out of one or more true alleles in STR typing is possible. We present a statistical model for estimating the per locus and overall probability of allelic drop-out using the results of all STR loci in the case sample as reference. The methodology of logistic regression is appropriate for this analysis, and we demonstrate how to incorporate this in a forensic genetic framework.
AB - In crime cases with available DNA evidence, the amount of DNA is often sparse due to the setting of the crime. In such cases, allelic drop-out of one or more true alleles in STR typing is possible. We present a statistical model for estimating the per locus and overall probability of allelic drop-out using the results of all STR loci in the case sample as reference. The methodology of logistic regression is appropriate for this analysis, and we demonstrate how to incorporate this in a forensic genetic framework.
U2 - 10.1016/j.fsigen.2009.02.002
DO - 10.1016/j.fsigen.2009.02.002
M3 - Journal article
C2 - 19647706
SN - 1872-4973
VL - 3
SP - 222
EP - 226
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
IS - 4
ER -
