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Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model
Nrupa Borkar, Daniel R. Andersson,
Mingshi Yang
,
Anette Müllertz
, René Holm,
Huiling Mu
9
Citationer (Scopus)
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Keyphrases
Rat Model
100%
Diester
100%
Parkinson's Disease
100%
Apomorphine
100%
Lipid-based Formulation
100%
Prodrug
15%
Behavioral Response
15%
Duration of Response
7%
Emulsion
7%
Steady Response
7%
Plasma Half-life
7%
Lipid-based
7%
Orally Administered
7%
Sustained Drug Release
7%
High Dose
7%
Symptomatology
7%
Self-emulsifying Drug Delivery Systems (SEDDS)
7%
Oral Delivery
7%
Model Simulating
7%
Pharmacology, Toxicology and Pharmaceutical Science
Rat Model
100%
Parkinson's Disease
100%
Apomorphine
100%
Prodrug
15%
Symptomatology
7%
First Pass Effect
7%
Drug Delivery System
7%
Oxidopamine
7%
Drug Release
7%