Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens

Natalia Mroczek-Sosnowska; Monika Lukasiewicz; Dobrochna Adamek; Maciej Kamaszewski; Jan Niemiec; Agnieszka  Wnuk-Gnich; Abdullah Talal Abdullah Skot; André Chwalibog; Ewa Sawosz

doi:10.1080/1745039X.2017.1331619

Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens

Natalia Mroczek-Sosnowska, Monika Lukasiewicz, Dobrochna Adamek, Maciej Kamaszewski, Jan Niemiec, Agnieszka Wnuk-Gnich, Abdullah Talal Abdullah Skot, André Chwalibog, Ewa Sawosz

15 Citationer (Scopus)

Abstract

The objective of this study was to evaluate bone resistance after in ovo administration of copper nanoparticles (NanoCu) and to determine the number of cells positive for proliferating cell nuclear antigen (PCNA) in the femoral bones of broiler chickens (n = 12 per group). The study demonstrated that femoral bones from the NanoCu group were characterised by a higher weight and volume and by significantly greater resistance to fractures compared to the Control group. NanoCu promoted the proliferation of PCNA-positive cells in the long bones of chickens. A significantly higher number of PCNA-positive cells in the bones of birds in the NanoCu group compared with the Control group (137 and 122, respectively) indicate a stimulatory effect during embryogenesis. Considering the improvement in bone resistance to fractures and the effect of NanoCu on the number of PCNA-positive cells in femoral bones, NanoCu may be an alternative agent to minimise the ever-present problem of weak bones in broiler chickens.

Originalsprog	Engelsk
Tidsskrift	Archives of Animal Nutrition
Vol/bind	71
Udgave nummer	4
Sider (fra-til)	327-332
Antal sider	6
ISSN	1745-039X
DOI	https://doi.org/10.1080/1745039X.2017.1331619
Status	Udgivet - 4 jul. 2017

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10.1080/1745039X.2017.1331619

Citationsformater

Mroczek-Sosnowska, N., Lukasiewicz, M., Adamek, D., Kamaszewski, M., Niemiec, J., Wnuk-Gnich, A., Skot, A. T. A., Chwalibog, A., & Sawosz, E. (2017). Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens. Archives of Animal Nutrition, 71(4), 327-332. https://doi.org/10.1080/1745039X.2017.1331619

Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens. / Mroczek-Sosnowska, Natalia; Lukasiewicz, Monika; Adamek, Dobrochna et al.
I: Archives of Animal Nutrition, Bind 71, Nr. 4, 04.07.2017, s. 327-332.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Mroczek-Sosnowska, N, Lukasiewicz, M, Adamek, D, Kamaszewski, M, Niemiec, J, Wnuk-Gnich, A, Skot, ATA , Chwalibog, A & Sawosz, E 2017, 'Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens', Archives of Animal Nutrition, bind 71, nr. 4, s. 327-332. https://doi.org/10.1080/1745039X.2017.1331619

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abstract = "The objective of this study was to evaluate bone resistance after in ovo administration of copper nanoparticles (NanoCu) and to determine the number of cells positive for proliferating cell nuclear antigen (PCNA) in the femoral bones of broiler chickens (n = 12 per group). The study demonstrated that femoral bones from the NanoCu group were characterised by a higher weight and volume and by significantly greater resistance to fractures compared to the Control group. NanoCu promoted the proliferation of PCNA-positive cells in the long bones of chickens. A significantly higher number of PCNA-positive cells in the bones of birds in the NanoCu group compared with the Control group (137 and 122, respectively) indicate a stimulatory effect during embryogenesis. Considering the improvement in bone resistance to fractures and the effect of NanoCu on the number of PCNA-positive cells in femoral bones, NanoCu may be an alternative agent to minimise the ever-present problem of weak bones in broiler chickens.",

author = "Natalia Mroczek-Sosnowska and Monika Lukasiewicz and Dobrochna Adamek and Maciej Kamaszewski and Jan Niemiec and Agnieszka Wnuk-Gnich and Skot, {Abdullah Talal Abdullah} and Andr{\'e} Chwalibog and Ewa Sawosz",

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AU - Mroczek-Sosnowska, Natalia

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AU - Adamek, Dobrochna

AU - Kamaszewski, Maciej

AU - Niemiec, Jan

AU - Wnuk-Gnich, Agnieszka

AU - Skot, Abdullah Talal Abdullah

AU - Chwalibog, André

AU - Sawosz, Ewa

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N2 - The objective of this study was to evaluate bone resistance after in ovo administration of copper nanoparticles (NanoCu) and to determine the number of cells positive for proliferating cell nuclear antigen (PCNA) in the femoral bones of broiler chickens (n = 12 per group). The study demonstrated that femoral bones from the NanoCu group were characterised by a higher weight and volume and by significantly greater resistance to fractures compared to the Control group. NanoCu promoted the proliferation of PCNA-positive cells in the long bones of chickens. A significantly higher number of PCNA-positive cells in the bones of birds in the NanoCu group compared with the Control group (137 and 122, respectively) indicate a stimulatory effect during embryogenesis. Considering the improvement in bone resistance to fractures and the effect of NanoCu on the number of PCNA-positive cells in femoral bones, NanoCu may be an alternative agent to minimise the ever-present problem of weak bones in broiler chickens.

AB - The objective of this study was to evaluate bone resistance after in ovo administration of copper nanoparticles (NanoCu) and to determine the number of cells positive for proliferating cell nuclear antigen (PCNA) in the femoral bones of broiler chickens (n = 12 per group). The study demonstrated that femoral bones from the NanoCu group were characterised by a higher weight and volume and by significantly greater resistance to fractures compared to the Control group. NanoCu promoted the proliferation of PCNA-positive cells in the long bones of chickens. A significantly higher number of PCNA-positive cells in the bones of birds in the NanoCu group compared with the Control group (137 and 122, respectively) indicate a stimulatory effect during embryogenesis. Considering the improvement in bone resistance to fractures and the effect of NanoCu on the number of PCNA-positive cells in femoral bones, NanoCu may be an alternative agent to minimise the ever-present problem of weak bones in broiler chickens.

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Effect of copper nanoparticles administered in ovo on the activity of proliferating cells and on the resistance of femoral bones in broiler chickens

Abstract

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