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Distinguishing Truncated and Normal MUC1 Glycoform Targeting from Tn-MUC1-Specific CAR T Cells: Specificity Is the Key to Safety
Avery D Posey,
Henrik Clausen
, Carl H June
Glycomics Program
19
Citationer (Scopus)
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Keyphrases
Glycoform
100%
T Cell Specificity
100%
Chimeric Antigen Receptor T Cells (CAR-T)
100%
Mucin 1 (MUC1)
100%
Blood Cancer
66%
Solid Tumors
33%
ScFv Antibody
33%
Antitumor Effect
33%
Fragment Specific
33%
Clinical Activity
33%
Adenocarcinoma
33%
Genetically Modified T Cells
33%
Biochemistry, Genetics and Molecular Biology
Cell Specificity
100%
MUC1
100%
Chimeric Antigen Receptor
100%
T Cell
100%
Single-Chain Variable Fragment
33%
Pharmacology, Toxicology and Pharmaceutical Science
Mucin 1
100%
Single Chain Fragment Variable Antibody
33%
Solid Malignant Neoplasm
33%
Malignant Neoplasm
33%
Adenocarcinoma
33%