TY - JOUR
T1 - Computed Tomography (CT) Perfusion in Abdominal Cancer
T2 - Technical Aspects
AU - Hansen, Martin Lundsgaard
AU - Norling, Rikke
AU - Lauridsen, Carsten
AU - Fallentin, Eva Marie
AU - Jensen, Lene Bæksgaard
AU - Kofoed, Klaus Fuglsang
AU - Svendsen, Lars Bo
AU - Nielsen, Michael Bachmann
PY - 2013/6
Y1 - 2013/6
N2 - Computed Tomography (CT) Perfusion is an evolving method to visualize perfusion in organs and tissue. With the introduction of multidetector CT scanners, it is now possible to cover up to 16 cm in one rotation, and thereby making it possible to scan entire organs such as the liver with a fixed table position. Advances in reconstruction algorithms make it possible to reduce the radiation dose for each examination to acceptable levels. Regarding abdominal imaging, CT perfusion is still considered a research tool, but several studies have proven it as a reliable non-invasive technique for assessment of vascularity. CT perfusion has also been used for tumor characterization, staging of disease, response evaluation of newer drugs targeted towards angiogenesis and as a method for early detection of recurrence after radiation and embolization. There are several software solutions available on the market today based on different perfusion algorithms. However, there is no consensus on which protocol and algorithm to use for specific organs. In this OPEN article, the authors give an introduction to CT perfusion in abdominal imaging introducing technical aspects for calculation of perfusion parameters, and considerations on patient preparation. This article also contains clinical cases to illustrate the use of C perfusion in abdominal imaging.
AB - Computed Tomography (CT) Perfusion is an evolving method to visualize perfusion in organs and tissue. With the introduction of multidetector CT scanners, it is now possible to cover up to 16 cm in one rotation, and thereby making it possible to scan entire organs such as the liver with a fixed table position. Advances in reconstruction algorithms make it possible to reduce the radiation dose for each examination to acceptable levels. Regarding abdominal imaging, CT perfusion is still considered a research tool, but several studies have proven it as a reliable non-invasive technique for assessment of vascularity. CT perfusion has also been used for tumor characterization, staging of disease, response evaluation of newer drugs targeted towards angiogenesis and as a method for early detection of recurrence after radiation and embolization. There are several software solutions available on the market today based on different perfusion algorithms. However, there is no consensus on which protocol and algorithm to use for specific organs. In this OPEN article, the authors give an introduction to CT perfusion in abdominal imaging introducing technical aspects for calculation of perfusion parameters, and considerations on patient preparation. This article also contains clinical cases to illustrate the use of C perfusion in abdominal imaging.
U2 - 10.3390/diagnostics3020261
DO - 10.3390/diagnostics3020261
M3 - Journal article
SN - 2075-4418
VL - 3
SP - 261
EP - 270
JO - Diagnostics
JF - Diagnostics
ER -
