Abstract
Cobalamin and its binding protein, haptocorrin, are present in rat milk throughout the lactation period. The concentration of cobalamin is approximately 0.3-times the concentration of the unsaturated binding protein. The concentration of the unsaturated cobalamin-binding protein varies between 18 nmol l-1 and 16 nmol l-1. The binding protein has a Stokes radius of 2.49 nm when saturated with cobalamin and 2.61 nm when unsaturated. It binds cobalamin over a broad range of pH and is able to bind cobinamide also. With immunohistochemistry, we find haptocorrin immunoreactivity in the mammary glands and in the sebaceous glands of the nipple.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Scandinavian Journal of Clinical & Laboratory Investigation |
| Vol/bind | 49 |
| Udgave nummer | 6 |
| Sider (fra-til) | 529-35 |
| Antal sider | 7 |
| ISSN | 0036-5513 |
| Status | Udgivet - okt. 1989 |