Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis

C P Hersh, Morten Dahl, N P Ly, C S Berkey, B G Nordestgaard, E K Silverman

    144 Citationer (Scopus)

    Abstract

    Severe alpha(1)-antitrypsin deficiency, usually related to homozygosity for the protease inhibitor (PI) Z allele, is a proven genetic risk factor for chronic obstructive pulmonary disease (COPD). The risk of COPD in PI MZ heterozygous individuals is controversial.
    OriginalsprogEngelsk
    TidsskriftThorax
    Vol/bind59
    Udgave nummer10
    Sider (fra-til)843-9
    Antal sider7
    ISSN0040-6376
    DOI
    StatusUdgivet - okt. 2004

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