Childhood asthma after bacterial colonization of the airway in neonates

H. Bisgaard; M.N. Hermansen; F. Buchvald; L. Loland; L.B. Halkjaer; Klaus Bønnelykke; Marie Sørensen Brasholt; A. Heltberg; N.H. Vissing; S.V. Thorsen; M. Stage; C.B. Pipper; Hans Bisgaard; Mette Northman Hermansen; Frederik Buchvald; Lotte Loland; Liselotte Brydensholt Halkjaer; Klaus Bønnelykke; Martin Brasholt; Andreas Heltberg; Nadja Hawwa Vissing; Sannie Vester Thorsen; Malene Stage; Christian Bressen Pipper

doi:http://dx.doi.org/10.1056/NEJMoa052632

Childhood asthma after bacterial colonization of the airway in neonates

H. Bisgaard, M.N. Hermansen, F. Buchvald, L. Loland, L.B. Halkjaer, Klaus Bønnelykke, Marie Sørensen Brasholt, A. Heltberg, N.H. Vissing, S.V. Thorsen, M. Stage, C.B. Pipper, Hans Bisgaard, Mette Northman Hermansen, Frederik Buchvald, Lotte Loland, Liselotte Brydensholt Halkjaer, Klaus Bønnelykke, Martin Brasholt, Andreas HeltbergNadja Hawwa Vissing, Sannie Vester Thorsen, Malene Stage, Christian Bressen Pipper

Institut for Klinisk Medicin

660 Citationer (Scopus)

Abstract

Pathological features of the airway in young children with severe recurrent wheeze suggest an association between bacterial colonization and the initiating events of early asthma. We conducted a study to investigate a possible association between bacterial colonization of the hypopharynx in asymptomatic neonates and later development of recurrent wheeze, asthma, and allergy during the first 5 years of life.

Originalsprog	Engelsk
Tidsskrift	New England Journal of Medicine
Vol/bind	357
Udgave nummer	15
Sider (fra-til)	1487-95
Antal sider	9
ISSN	0028-4793
DOI	https://doi.org/10.1056/NEJMoa052632
Status	Udgivet - 11 okt. 2007

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http://dx.doi.org/10.1056/NEJMoa052632

Citationsformater

Bisgaard, H., Hermansen, M. N., Buchvald, F., Loland, L., Halkjaer, L. B., Bønnelykke, K., Brasholt, M. S., Heltberg, A., Vissing, N. H., Thorsen, S. V., Stage, M., Pipper, C. B., Bisgaard, H., Hermansen, M. N., Buchvald, F., Loland, L., Halkjaer, L. B., Bønnelykke, K., Brasholt, M., ... Pipper, C. B. (2007). Childhood asthma after bacterial colonization of the airway in neonates. New England Journal of Medicine, 357(15), 1487-95. https://doi.org/10.1056/NEJMoa052632

Bisgaard, H, Hermansen, MN, Buchvald, F, Loland, L, Halkjaer, LB, Bønnelykke, K, Brasholt, MS, Heltberg, A, Vissing, NH, Thorsen, SV, Stage, M, Pipper, CB, Bisgaard, H, Hermansen, MN, Buchvald, F, Loland, L, Halkjaer, LB, Bønnelykke, K, Brasholt, M, Heltberg, A, Vissing, NH, Thorsen, SV, Stage, M & Pipper, CB 2007, 'Childhood asthma after bacterial colonization of the airway in neonates', New England Journal of Medicine, bind 357, nr. 15, s. 1487-95. https://doi.org/10.1056/NEJMoa052632

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title = "Childhood asthma after bacterial colonization of the airway in neonates",

abstract = "Pathological features of the airway in young children with severe recurrent wheeze suggest an association between bacterial colonization and the initiating events of early asthma. We conducted a study to investigate a possible association between bacterial colonization of the hypopharynx in asymptomatic neonates and later development of recurrent wheeze, asthma, and allergy during the first 5 years of life.",

author = "H. Bisgaard and M.N. Hermansen and F. Buchvald and L. Loland and L.B. Halkjaer and Klaus B{\o}nnelykke and Brasholt, {Marie S{\o}rensen} and A. Heltberg and N.H. Vissing and S.V. Thorsen and M. Stage and C.B. Pipper and Hans Bisgaard and Hermansen, {Mette Northman} and Frederik Buchvald and Lotte Loland and Halkjaer, {Liselotte Brydensholt} and Klaus B{\o}nnelykke and Martin Brasholt and Andreas Heltberg and Vissing, {Nadja Hawwa} and Thorsen, {Sannie Vester} and Malene Stage and Pipper, {Christian Bressen}",

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doi = "http://dx.doi.org/10.1056/NEJMoa052632",

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TY - JOUR

T1 - Childhood asthma after bacterial colonization of the airway in neonates

AU - Bisgaard, H.

AU - Hermansen, M.N.

AU - Buchvald, F.

AU - Loland, L.

AU - Halkjaer, L.B.

AU - Bønnelykke, Klaus

AU - Brasholt, Marie Sørensen

AU - Heltberg, A.

AU - Vissing, N.H.

AU - Thorsen, S.V.

AU - Stage, M.

AU - Pipper, C.B.

AU - Bisgaard, Hans

AU - Hermansen, Mette Northman

AU - Buchvald, Frederik

AU - Loland, Lotte

AU - Halkjaer, Liselotte Brydensholt

AU - Bønnelykke, Klaus

AU - Brasholt, Martin

AU - Heltberg, Andreas

AU - Vissing, Nadja Hawwa

AU - Thorsen, Sannie Vester

AU - Stage, Malene

AU - Pipper, Christian Bressen

PY - 2007/10/11

Y1 - 2007/10/11

N2 - Pathological features of the airway in young children with severe recurrent wheeze suggest an association between bacterial colonization and the initiating events of early asthma. We conducted a study to investigate a possible association between bacterial colonization of the hypopharynx in asymptomatic neonates and later development of recurrent wheeze, asthma, and allergy during the first 5 years of life.

AB - Pathological features of the airway in young children with severe recurrent wheeze suggest an association between bacterial colonization and the initiating events of early asthma. We conducted a study to investigate a possible association between bacterial colonization of the hypopharynx in asymptomatic neonates and later development of recurrent wheeze, asthma, and allergy during the first 5 years of life.

U2 - http://dx.doi.org/10.1056/NEJMoa052632

DO - http://dx.doi.org/10.1056/NEJMoa052632

M3 - Journal article

SN - 0028-4793

VL - 357

SP - 1487

EP - 1495

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 15

ER -

Childhood asthma after bacterial colonization of the airway in neonates

Abstract

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