CHARACTERIZATION OF RENAL BLOOD FLOW REGULATION BASED ON WAVELET COEFFICIENTS

TY - JOUR

T1 - CHARACTERIZATION OF RENAL BLOOD FLOW REGULATION BASED ON WAVELET COEFFICIENTS

AU - Pavlov, Alexay

AU - Pavlova, Olga

AU - Mosekilde, Erik

AU - Sosnovtseva, Olga

PY - 2010/9

Y1 - 2010/9

N2 - The purpose of this study is to demonstrate the possibility of revealing new characteristic features of renal blood flow autoregulation in healthy and pathological states through the application of discrete wavelet transforms to experimental time series for normotensive and hypertensive rats. A reduction in the variability of the wavelet coefficients in hypertension is observed at both the microscopic level of the blood flow in efferent arterioles of individual nephrons and at the macroscopic level of the blood pressure in the main arteries. The reduction is manifest in both of the main frequency domains of nephron autoregulation and is likely to reflect a reduced flexibility of the cardiovascular system during hypertension.

AB - The purpose of this study is to demonstrate the possibility of revealing new characteristic features of renal blood flow autoregulation in healthy and pathological states through the application of discrete wavelet transforms to experimental time series for normotensive and hypertensive rats. A reduction in the variability of the wavelet coefficients in hypertension is observed at both the microscopic level of the blood flow in efferent arterioles of individual nephrons and at the macroscopic level of the blood pressure in the main arteries. The reduction is manifest in both of the main frequency domains of nephron autoregulation and is likely to reflect a reduced flexibility of the cardiovascular system during hypertension.

U2 - 10.1142/s0219477510000204

DO - 10.1142/s0219477510000204

M3 - Journal article

SN - 0219-4775

VL - 9

SP - 259

EP - 270

JO - Fluctuation and Noise Letters

JF - Fluctuation and Noise Letters

IS - 3

ER -