Abstract
Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3 months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co-morbidities, body mass index ≥25 kg/m2, unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Acta Obstetricia et Gynecologica Scandinavica |
| Vol/bind | 94 |
| Udgave nummer | 8 |
| Sider (fra-til) | 898-903 |
| Antal sider | 6 |
| ISSN | 0001-6349 |
| DOI | |
| Status | Udgivet - 1 aug. 2015 |