Catalytic stereospecific O-glycosylation

Karolina Kowalska; Christian Marcus Pedersen

doi:10.1039/c6cc10076g

Catalytic stereospecific O-glycosylation

Karolina Kowalska, Christian Marcus Pedersen

Kemisk Institut

15 Citationer (Scopus)

Abstract

A new simple protocol, using TMSNTf2 or Tf2NH as the catalyst, for the activation of trichloroacetimidate donors is described. This O-glycosylation proceeds with stereospecific inversion of the donor configuration. The scope of the protocol has been investigated using common glycosyl donors reacting with simple alcohols as well as sugar acceptors

Originalsprog	Engelsk
Tidsskrift	Chemical Communications
Vol/bind	53
Udgave nummer	12
Sider (fra-til)	2040-2043
Antal sider	4
ISSN	1359-7345
DOI	https://doi.org/10.1039/c6cc10076g
Status	Udgivet - 2017

Adgang til dokumentet

10.1039/c6cc10076g

Citationsformater

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title = "Catalytic stereospecific O-glycosylation",

abstract = "A new simple protocol, using TMSNTf2 or Tf2NH as the catalyst, for the activation of trichloroacetimidate donors is described. This O-glycosylation proceeds with stereospecific inversion of the donor configuration. The scope of the protocol has been investigated using common glycosyl donors reacting with simple alcohols as well as sugar acceptors",

author = "Karolina Kowalska and Pedersen, {Christian Marcus}",

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AU - Kowalska, Karolina

AU - Pedersen, Christian Marcus

PY - 2017

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AB - A new simple protocol, using TMSNTf2 or Tf2NH as the catalyst, for the activation of trichloroacetimidate donors is described. This O-glycosylation proceeds with stereospecific inversion of the donor configuration. The scope of the protocol has been investigated using common glycosyl donors reacting with simple alcohols as well as sugar acceptors

U2 - 10.1039/c6cc10076g

DO - 10.1039/c6cc10076g

M3 - Journal article

C2 - 28125110

SN - 1359-7345

VL - 53

SP - 2040

EP - 2043

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -