Authentication and assessment of contamination in ancient DNA

Gabriel Renaud; Mikkel Schubert; Susanna Sawyer; Ludovic Orlando

doi:10.1007/978-1-4939-9176-1_17

Authentication and assessment of contamination in ancient DNA

Gabriel Renaud, Mikkel Schubert, Susanna Sawyer, Ludovic Orlando^*

^*Corresponding author af dette arbejde

3 Citationer (Scopus)

Abstract

Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.

Originalsprog	Engelsk
Titel	Ancient DNA : Methods and Protocols
Redaktører	Beth Shapiro, Axel Barlow, Peter D. Heintzman, Michael Hofreiter, Johanna L. A. Paijmans, André E. R. Soares
Antal sider	32
Forlag	Humana Press
Publikationsdato	2019
Udgave	2. ed.
Sider	163-194
Kapitel	17
ISBN (Trykt)	978-1-4939-9175-4
ISBN (Elektronisk)	978-1-4939-9176-1
DOI	https://doi.org/10.1007/978-1-4939-9176-1_17
Status	Udgivet - 2019

Navn	Methods in Molecular Biology
Vol/bind	1963
ISSN	1064-3745

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10.1007/978-1-4939-9176-1_17

Renaud-AuthenticationChapter-AcceptedLicens: CC BY-NC-SA

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Renaud, G., Schubert, M., Sawyer, S., & Orlando, L. (2019). Authentication and assessment of contamination in ancient DNA. I B. Shapiro, A. Barlow, P. D. Heintzman, M. Hofreiter, J. L. A. Paijmans, & A. E. R. Soares (red.), Ancient DNA: Methods and Protocols (2. ed. udg., s. 163-194). Humana Press. Methods in Molecular Biology Bind 1963 https://doi.org/10.1007/978-1-4939-9176-1_17

Authentication and assessment of contamination in ancient DNA. / Renaud, Gabriel; Schubert, Mikkel; Sawyer, Susanna et al.

Ancient DNA: Methods and Protocols. red. / Beth Shapiro; Axel Barlow; Peter D. Heintzman; Michael Hofreiter; Johanna L. A. Paijmans; André E. R. Soares. 2. ed. udg. Humana Press, 2019. s. 163-194 (Methods in Molecular Biology, Bind 1963).

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

Renaud, Gabriel ; Schubert, Mikkel ; Sawyer, Susanna et al. / Authentication and assessment of contamination in ancient DNA. Ancient DNA: Methods and Protocols. red. / Beth Shapiro ; Axel Barlow ; Peter D. Heintzman ; Michael Hofreiter ; Johanna L. A. Paijmans ; André E. R. Soares. 2. ed. udg. Humana Press, 2019. s. 163-194 (Methods in Molecular Biology, Bind 1963).

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Authentication and assessment of contamination in ancient DNA

Abstract

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