Arvelige cancersyndromer

Anne-Marie Axø Gerdes

Arvelige cancersyndromer

Abstract

Hereditary cancer syndromes are characterized by increased risk of cancers but other symptoms can also be seen. Germline mutations usually cause a high cancer risk but more moderate risk genes are being identified. A negative mutation screening cannot exclude a hereditary cancer syndrome, since it is not possible to analyse all genes. Genetic diagnostics are now part of clinical management and new technology such as next generation sequencing and high-throughput screening are being implemented in clinical settings. This will also impose new challenges such as identification and interpretation of mutations with unknown significance.

Bidragets oversatte titel	[Hereditary cancer syndromes]
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	173
Udgave nummer	34
Sider (fra-til)	2035-8
Antal sider	4
ISSN	0041-5782
Status	Udgivet - aug. 2011

FN’s Verdensmål

Dette resultat bidrager til følgende verdensmål

Citationsformater

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AB - Hereditary cancer syndromes are characterized by increased risk of cancers but other symptoms can also be seen. Germline mutations usually cause a high cancer risk but more moderate risk genes are being identified. A negative mutation screening cannot exclude a hereditary cancer syndrome, since it is not possible to analyse all genes. Genetic diagnostics are now part of clinical management and new technology such as next generation sequencing and high-throughput screening are being implemented in clinical settings. This will also impose new challenges such as identification and interpretation of mutations with unknown significance.

M3 - Tidsskriftartikel

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EP - 2038

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Arvelige cancersyndromer

Abstract

FN’s Verdensmål

Fingeraftryk

Citationsformater