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Approaches to diagnose DNA mismatch repair gene defects in cancer
Javier Peña-Diaz,
Lene Juel Rasmussen
Molecular Aging Program
Center for Sund Aldring
Damage and Repair
18
Citationer (Scopus)
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Keyphrases
In Cancer
100%
Gene Defects
100%
Mismatch Repair Genes
100%
DNA Mismatch Repair Genes
100%
Mismatch Repair
83%
Variants of Uncertain Significance
33%
Lynch Syndrome
33%
Hereditary Colorectal Cancer Syndromes
33%
Human Disease
33%
Pathogenicity
33%
Gene Alteration
16%
Genetic Inactivation
16%
Non-hereditary
16%
Deficient Mismatch Repair (dMMR)
16%
Mutation Load
16%
Cancer Genetics
16%
Personalized Genomics
16%
Cancer Risk
16%
Insertion-deletion
16%
DNA Repair Pathways
16%
Germline mutation
16%
Rapid Assessment
16%
Treatment Choice
16%
Associated Risk
16%
Replicative Helicase
16%
Cancer Predisposition
16%
Cancer Development
16%
Hypermutation
16%
Nucleotide Synthesis
16%
Colorectal Cancer Patients
16%
Epigenetic Modification
16%
Tumorigenesis
16%
Mispair
16%
Well-defined
16%
Left behind
16%
Diagnostic Tool
16%
Pharmacology, Toxicology and Pharmaceutical Science
Hereditary Nonpolyposis Colorectal Cancer
100%
Malignant Neoplasm
100%
Diseases
75%
Pathogenicity
50%
Colon Carcinoma
25%
Carcinogenesis
25%
Neoplasm
25%
Cancer Susceptibility
25%
Colorectal Carcinoma
25%
Medicine and Dentistry
Malignant Neoplasm
100%
DNA Mismatch Repair
100%
Gene Repair
38%
Hereditary Nonpolyposis Colorectal Cancer
30%
Diseases
23%
Pathogenicity
15%
Polymerase
7%
Neoplasm
7%
Mutational Load
7%
Colorectal Carcinoma
7%
Cancer Susceptibility
7%
DNA Repair
7%
Chemotherapy
7%
Cancer
7%
Germline Mutation
7%
Indel Mutation
7%
Diagnosis
7%
Carcinogenesis
7%
Colon Carcinoma
7%
Gene Mutation
7%
Rapid Assessment
7%
Immunology and Microbiology
Mismatch Repair
100%
Mismatch DNA Repair
100%
Pathogenicity
16%
Germline Mutation
8%
Genetic Predisposition
8%
Gene Mutation
8%
DNA Repair
8%
Indel Mutation
8%
Mutational Load
8%
Biochemistry, Genetics and Molecular Biology
DNA Mismatch Repair
100%
Gene Repair
38%
Epigenetics
15%
Germline Mutation
7%
Carcinogenesis
7%
Genetic Predisposition
7%
Genomics
7%
Mutational Load
7%
DNA Repair
7%
Gene Mutation
7%
Polymerase
7%
Indel
7%