Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material

E M Pinholt; G Bang; H R Haanaes

Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material

E M Pinholt, G Bang, H R Haanaes

Sektion 04

15 Citationer (Scopus)

Abstract

The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized, lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither an osteoinductive nor an osteoconductive effect. The newly formed bone induced from the implanted allogenic, demineralized, lyophilized dentin or bone was never found in close contact with the HA and did not incorporate the implant.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Dental Research
Vol/bind	99
Udgave nummer	1
Sider (fra-til)	64-74
Antal sider	11
ISSN	0029-845X
Status	Udgivet - 1 feb. 1991

Citationsformater

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title = "Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material",

abstract = "The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized, lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither an osteoinductive nor an osteoconductive effect. The newly formed bone induced from the implanted allogenic, demineralized, lyophilized dentin or bone was never found in close contact with the HA and did not incorporate the implant.",

keywords = "Abdominal Muscles, Alveolar Ridge Augmentation, Animals, Bone Transplantation, Connective Tissue, Dentin, Durapatite, Foreign-Body Reaction, Freeze Drying, Hydroxyapatites, Male, Maxilla, Osteogenesis, Prostheses and Implants, Rats, Rats, Inbred Strains",

author = "Pinholt, {E M} and G Bang and Haanaes, {H R}",

year = "1991",

month = feb,

day = "1",

language = "English",

volume = "99",

pages = "64--74",

journal = "Scandinavian Journal of Dental Research",

issn = "0029-845X",

publisher = "Munksgaard ",

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TY - JOUR

T1 - Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material

AU - Pinholt, E M

AU - Bang, G

AU - Haanaes, H R

PY - 1991/2/1

Y1 - 1991/2/1

N2 - The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized, lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither an osteoinductive nor an osteoconductive effect. The newly formed bone induced from the implanted allogenic, demineralized, lyophilized dentin or bone was never found in close contact with the HA and did not incorporate the implant.

AB - The purpose of this study was to examine if increased bony ingrowth developed when hydroxylapatite was implanted together with an osteoinductive substrate. Dense hydroxylapatite granules (HA) (Calcitite, Calcitek, San Diego, CA, USA) were mixed with equal volumes of allogenic, demineralized, lyophilized dentin or bone and implanted subperiosteally for alveolar ridge augmentation purposes and heterotopically in the abdominal muscles in rats. Light microscopic evaluation revealed that HA was surrounded by fibrous connective tissue containing foreign body giant cells and it had neither an osteoinductive nor an osteoconductive effect. The newly formed bone induced from the implanted allogenic, demineralized, lyophilized dentin or bone was never found in close contact with the HA and did not incorporate the implant.

KW - Abdominal Muscles

KW - Alveolar Ridge Augmentation

KW - Animals

KW - Bone Transplantation

KW - Connective Tissue

KW - Dentin

KW - Durapatite

KW - Foreign-Body Reaction

KW - Freeze Drying

KW - Hydroxyapatites

KW - Male

KW - Maxilla

KW - Osteogenesis

KW - Prostheses and Implants

KW - Rats

KW - Rats, Inbred Strains

M3 - Journal article

C2 - 1646480

SN - 0029-845X

VL - 99

SP - 64

EP - 74

JO - Scandinavian Journal of Dental Research

JF - Scandinavian Journal of Dental Research

IS - 1

ER -

Alveolar ridge augmentation in rats by combined hydroxylapatite and osteoinductive material

Abstract

Fingeraftryk

Citationsformater