Alkamides from Phyllanthus fraternus

A A Sittie; E Lemmich; C E Olsen; L Hviid; S Brøgger Christensen

Alkamides from Phyllanthus fraternus

A A Sittie, E Lemmich, C E Olsen, L Hviid, S Brøgger Christensen

31 Citationer (Scopus)

Abstract

Udgivelsesdato: 1998-Mar

Originalsprog	Engelsk
Tidsskrift	Planta Medica
Vol/bind	64
Udgave nummer	2
Sider (fra-til)	192-3
Antal sider	1
ISSN	0032-0943
Status	Udgivet - 1998

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Citationsformater

@article{b2da03c0a06b11dd86a6000ea68e967b,

title = "Alkamides from Phyllanthus fraternus",

abstract = "Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.",

author = "Sittie, {A A} and E Lemmich and Olsen, {C E} and L Hviid and {Br{\o}gger Christensen}, S",

note = "Keywords: Amides; Animals; Antiprotozoal Agents; Humans; Leishmania major; Lymphocyte Activation; Lymphocytes; Plants, Medicinal; Plasmodium falciparum",

year = "1998",

language = "English",

volume = "64",

pages = "192--3",

journal = "Planta Medica",

issn = "0032-0943",

publisher = "GeorgThieme Verlag",

number = "2",

}

TY - JOUR

T1 - Alkamides from Phyllanthus fraternus

AU - Sittie, A A

AU - Lemmich, E

AU - Olsen, C E

AU - Hviid, L

AU - Brøgger Christensen, S

N1 - Keywords: Amides; Animals; Antiprotozoal Agents; Humans; Leishmania major; Lymphocyte Activation; Lymphocytes; Plants, Medicinal; Plasmodium falciparum

PY - 1998

Y1 - 1998

N2 - Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.

AB - Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.

M3 - Journal article

C2 - 9525113

SN - 0032-0943

VL - 64

SP - 192

EP - 193

JO - Planta Medica

JF - Planta Medica

IS - 2

ER -

Alkamides from Phyllanthus fraternus

Abstract

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