A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

Maria E Due-Hansen; Sunil K Pandey; Elisabeth Christiansen; Rikke Andersen; Steffen V F Hansen; Trond Ulven

doi:10.1039/c5ob02129d

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

Maria E Due-Hansen, Sunil K Pandey, Elisabeth Christiansen, Rikke Andersen, Steffen V F Hansen, Trond Ulven

41 Citationer (Scopus)

Abstract

A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard methods failed.

Originalsprog	Engelsk
Tidsskrift	Organic & Biomolecular Chemistry
Vol/bind	14
Udgave nummer	2
Sider (fra-til)	430-433
Antal sider	4
ISSN	1477-0520
DOI	https://doi.org/10.1039/c5ob02129d
Status	Udgivet - 2016
Udgivet eksternt	Ja

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10.1039/c5ob02129d

c5ob02129dForlagets udgivne version, 302 KBLicens: CC BY

Citationsformater

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abstract = "A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard methods failed.",

author = "Due-Hansen, {Maria E} and Pandey, {Sunil K} and Elisabeth Christiansen and Rikke Andersen and Hansen, {Steffen V F} and Trond Ulven",

year = "2016",

doi = "10.1039/c5ob02129d",

language = "English",

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pages = "430--433",

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publisher = "Royal Society of Chemistry",

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T1 - A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

AU - Due-Hansen, Maria E

AU - Pandey, Sunil K

AU - Christiansen, Elisabeth

AU - Andersen, Rikke

AU - Hansen, Steffen V F

AU - Ulven, Trond

PY - 2016

Y1 - 2016

N2 - A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard methods failed.

AB - A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard methods failed.

U2 - 10.1039/c5ob02129d

DO - 10.1039/c5ob02129d

M3 - Journal article

SN - 1477-0520

VL - 14

SP - 430

EP - 433

JO - Organic & Biomolecular Chemistry

JF - Organic & Biomolecular Chemistry

IS - 2

ER -

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

Abstract

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