A novel pseudo-complementary PNA G-C base pair

Anne G. Olsen; Otto Dahl; Asger Bjørn Petersen; John Nielsen; Peter E. Nielsen

doi:10.4161/adna.2.1.15554

A novel pseudo-complementary PNA G-C base pair

Anne G. Olsen, Otto Dahl, Asger Bjørn Petersen, John Nielsen, Peter E. Nielsen

7 Citationer (Scopus)

Abstract

Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-c base pair consisting of the unnatural nucleobases A/6-methoxy-2,6-diaminopurine (previously described in a DNA context) and A/4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs).

Originalsprog	Engelsk
Tidsskrift	Artificial DNA
Vol/bind	2
Udgave nummer	1
Sider (fra-til)	33-37
Antal sider	5
ISSN	1949-095X
DOI	https://doi.org/10.4161/adna.2.1.15554
Status	Udgivet - 2011

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10.4161/adna.2.1.15554

Citationsformater

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title = "A novel pseudo-complementary PNA G-C base pair",

abstract = "Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-c base pair consisting of the unnatural nucleobases A/6-methoxy-2,6-diaminopurine (previously described in a DNA context) and A/4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs).",

author = "Olsen, {Anne G.} and Otto Dahl and Petersen, {Asger Bj{\o}rn} and John Nielsen and Nielsen, {Peter E.}",

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T1 - A novel pseudo-complementary PNA G-C base pair

AU - Olsen, Anne G.

AU - Dahl, Otto

AU - Petersen, Asger Bjørn

AU - Nielsen, John

AU - Nielsen, Peter E.

PY - 2011

Y1 - 2011

N2 - Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-c base pair consisting of the unnatural nucleobases A/6-methoxy-2,6-diaminopurine (previously described in a DNA context) and A/4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs).

AB - Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-c base pair consisting of the unnatural nucleobases A/6-methoxy-2,6-diaminopurine (previously described in a DNA context) and A/4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs).

U2 - 10.4161/adna.2.1.15554

DO - 10.4161/adna.2.1.15554

M3 - Journal article

C2 - 21686250

SN - 1949-095X

VL - 2

SP - 33

EP - 37

JO - Artificial DNA

JF - Artificial DNA

IS - 1

ER -

A novel pseudo-complementary PNA G-C base pair

Abstract

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