γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket

Lucia Tamborini, Veronica Nicosia, Paola Conti, Federica Dall'Oglio, Carlo De Micheli, Birgitte Nielsen, Anders A. Jensen, Darryl S Pickering, Andrea Pinto

    1 Citationer (Scopus)

    Abstract

    γ-Glutamyl-dipeptides, built by condensing the distal carboxylate of L-Glu (or D-Glu) onto a series of differently functionalized amino acids, were prepared and used as tools for rapidly probing the stereoelectronic properties of iGluRs, searching for subtype-selective ligands.
    OriginalsprogEngelsk
    TidsskriftTetrahedron
    Vol/bind72
    Udgave nummer51
    Sider (fra-til)8586-8492
    Antal sider7
    ISSN0040-4020
    DOI
    StatusUdgivet - 1 dec. 2016

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