Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
The overall aim of my research is to understand how oxidative modifications impact on the structure and function of proteins. I am also investigating how these types of modifications influence the formation of supramolecular assemblies and protein aggregates.
A major focus area is the development of mass-spectrometry-based methodologies for qualitative and quantitative analysis of oxidative protein modifications, including intra- and intermolecular cross-links. I also have a long-standing interest in thioredoxins and thiol-disulphide exchange reactions.
Emneord
- Det Sundhedsvidenskabelige Fakultet
- Protein oxidation, mass spectrometry, cross-linking, aggregation, supramolecular assemblies, proteomics
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Per Mårten Hägglund er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 6 Lignende profiler
-
Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hagglund, P., Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, M. J., 1 nov. 2019, I: Free Radical Biology and Medicine. 143, s. 375-386Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Copper ion / H2O2 oxidation of Cu/Zn-Superoxide dismutase: Implications for enzymatic activity and antioxidant action
Tiwari, M. K., Hägglund, P. M., Møller, I. M., Davies, M. J. & Bjerrum, M. J., sep. 2019, I: Redox Biology. 26, 15 s., 101262.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Expanding the citrullinome of synovial fibrinogen from rheumatoid arthritis patients
Sharma, M., Danigaard, D., Senolt, L., Svensson, B., Bay-Jensen, A-C., Nielsen, C. H. & Hägglund, P., 30 sep. 2019, I: Journal of Proteomics. 208, 103484.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]
Shu, N., Hagglund, P. M. & Davies, M., 1 aug. 2019, I: Free Radical Biology and Medicine. 139, S1, s. S9-S9 8.Publikation: Bidrag til tidsskrift › Konferenceartikel › Forskning
-
Tofacitinib and TPCA-1 exert chondroprotective effects on extracellular matrix turnover in bovine articular cartilage ex vivo
Kjelgaard-Petersen, C. F., Sharma, N., Kayed, A., Karsdal, M. A., Mobasheri, A., Hagglund, P., Bay-Jensen, A-C. & Thudium, C. S., jul. 2019, I: Biochemical Pharmacology. 165, s. 91-98Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, C. Y., Mariotti, M., Hammer, A., Hoefler, G., Hägglund, P., Malle, E., Wise, S. G. & Davies, M. J., 1 feb. 2018, I: Free Radical Biology & Medicine. 115, S1, s. 202-214 13 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
-
Identification and characterization of protein cross-links induced by oxidative reactions
Hagglund, P., Mariotti, M. & Davies, M. J., 3 aug. 2018, I: Expert Review of Proteomics. 15, 8, s. 665-681Publikation: Bidrag til tidsskrift › Review › peer review
-
Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation
Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, M. J. & Hagglund, P., 1 jun. 2018, I: Journal of Proteome Research. 17, 6, s. 2017-2027Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review