Olivier Thierry Taboureau

Publikation

Publikationer pr. år 2008 2013 2016 2017 2018 2019 2019

• 14 Tidsskriftartikel
• 1 Kommentar/debat
• 1 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1

  Briand, E., Thomsen, R., Linnet, K., Rasmussen, H. B., Brunak, S. & Taboureau, O., 29 jul. 2019, I: Molecules. 24, 15, 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • human CES1 protein 100%
  • Carboxylesterase 70%
  • machine learning 66%
  • Machine Learning 59%
  • drugs 52%
  1 Citationer (Scopus)

  26 Downloads (Pure)

• sAOP: linking chemical stressors to adverse outcomes pathway networks

  Aguayo-Orozco, A., Audouze, K., Siggaard, T., Barouki, R., Brunak, S. & Taboureau, O., 15 dec. 2019, I: Bioinformatics. 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Adverse Outcome Pathways 100%
  • Pathway 71%
  • Linking 63%
  • Toxicological Phenomena 29%
  • Wikis 22%
  5 Citationer (Scopus)

  4 Downloads (Pure)

• The use of systems biology in chemical risk assessment

  Aguayo-Orozco, A., Taboureau, O. & Brunak, S., 2019, I: Current Opinion in Toxicology. 15, s. 48-54 7 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Risk Assessment 100%
  • Systems Biology 98%
  • Adverse Outcome Pathways 68%
  • Toxicology 60%
  • Pharmacologic Actions 29%
  4 Citationer (Scopus)

  16 Downloads (Pure)
• 2018

  Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity

  Aguayo-Orozco, A., Bois, F. Y., Brunak, S. & Taboureau, O., 2018, I: Frontiers in Genetics. 9, s. 1-15 396.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Fatty Liver 100%
  • Gene Expression 84%
  • Adverse Outcome Pathways 77%
  • linolenic acid drug combination linoleic acid 77%
  • Liver 72%
  5 Citationer (Scopus)

  101 Downloads (Pure)

• Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes

  Grinberg, M., Stöber, R. M., Albrecht, W., Edlund, K., Schug, M., Godoy, P., Cadenas, C., Marchan, R., Lampen, A., Braeuning, A., Buhrke, T., Leist, M., Oberemm, A., Hellwig, B., Kamp, H., Gardner, I., Escher, S., Taboureau, O., Aguayo-Orozco, A., Sachinidis, A., & 3 flereEllinger-Ziegelbauer, H., Rahnenführer, J. & Hengstler, J. G., dec. 2018, I: Archives of Toxicology. 92, 12, s. 3517-3533 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Toxicogenetics 100%
  • Valproic Acid 96%
  • Directories 93%
  • Microarrays 71%
  • Hepatocytes 55%
  24 Citationer (Scopus)
• 2017

  Adverse outcome pathways: opportunities, limitations and open questions

  Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S. H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., Danen, E., van Ravenzwaay, B., Kamp, H., Gardner, I., Godoy, P., Bois, F. Y., Braeuning, A., Reif, R., Oesch, F., Drasdo, D., & 33 flereHöhme, S., Schwarz, M., Hartung, T., Braunbeck, T., Beltman, J., Vrieling, H., Sanz, F., Forsby, A., Gadaleta, D., Fisher, C., Kelm, J., Fluri, D., Ecker, G., Zdrazil, B., Terron, A., Jennings, P., van der Burg, B., Dooley, S., Meijer, A. H., Willighagen, E., Martens, M., Evelo, C., Mombelli, E., Taboureau, O., Mantovani, A., Hardy, B., Koch, B., Escher, S., van Thriel, C., Cadenas, C., Kroese, D., van de Water, B. & Hengstler, J. G., 1 nov. 2017, I: Archives of Toxicology. 91, 11, s. 3477-3505 29 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Adverse Outcome Pathways 100%
  • Toxicokinetics 86%
  • Plastic Property 69%
  • Pharmacological Metabolism 46%
  • Strength 38%
  153 Citationer (Scopus)

• Human Environmental Disease Network: A computational model to assess toxicology of contaminants

  Taboureau, O. & Audouze, K., 2017, I: Altex. 17, 2, s. 289-300

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Toxicology 100%
  • Animal Testing Alternatives 10%
  • Chlordan 10%
  • bisphenol A 7%
  • Systems Biology 7%
  14 Citationer (Scopus)

  56 Downloads (Pure)

• Nomenclature for alleles of the human carboxylesterase 1 gene

  INDICES Consortium, 1 jan. 2017, I: Pharmacogenetics and Genomics. 27, 2, s. 78-80 3 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

  4 Citationer (Scopus)
• 2016

  ChemProt-3.0: a global chemical biology diseases mapping

  Kringelum, J. V., Kjærulff, S. K., Brunak, S., Lund, O., Oprea, T. I. & Taboureau, O. T., 2016, I: Database: The Journal of Biological Databases and Curation. 2016, 7 s., bav123.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Proteins 100%
  • Biological Sciences 79%
  • Pharmacology 72%
  • Quantitative Structure-Activity Relationship 50%
  • Pharmacogenomic Testing 48%
  45 Citationer (Scopus)

  131 Downloads (Pure)

• In Silico Systems Pharmacology to Assess Drug's Therapeutic and Toxic Effects

  Orozco, A. A., Audouze, K., Brunak, S. & Taboureau, O., 1 dec. 2016, I: Current Pharmaceutical Design. 22, 46, s. 6895-6902 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Computer Simulation 100%
  • Therapeutic Uses 87%
  • Toxic 79%
  • Poisons 78%
  • Pharmacology 70%
  2 Citationer (Scopus)

  47 Downloads (Pure)

• Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches

  Nzabonimpa, G. S., Rasmussen, H. B., Brunak, S., Taboureau, O. & INDICES Consortium, 1 jun. 2016, I: Drug Metabolism and Personalized Therapy. 31, 2, s. 97-106 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • human CES1 protein 100%
  • Missense Mutation 54%
  • Computer Simulation 49%
  • Single Nucleotide Polymorphism 43%
  • Carboxylic Ester Hydrolases 34%
  3 Citationer (Scopus)
• 2014

  Solid-phase synthesis and biological evaluation of N-dipeptido L-homoserine lactones as quorum sensing activators

  Hansen, M. R., Le Quement, S. T., Jakobsen, T. H., Skovstrup, S., Taboureau, O., Tolker-Nielsen, T., Givskov, M. & Nielsen, T. E., 10 feb. 2014, I: ChemBioChem. 15, 3, s. 460-5 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • L-Homoserine Lactone 100%
  • homoserine lactone 82%
  • Solid-Phase Synthesis Techniques 80%
  • Quorum Sensing 63%
  • Signalling Molecule 63%
  5 Citationer (Scopus)
• 2013

  Identification of LasR ligands through a virtual screening approach

  Skovstrup, S., Le Quement, S. T., Hansen, T., Jakobsen, T. H., Harmsen, M., Tolker-Nielsen, T., Nielsen, T. E., Givskov, M. & Taboureau, O., jan. 2013, I: ChemMedChem. 8, 1, s. 157-63 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • N-(3-Oxododecanoyl)-L-Homoserine Lactone 100%
  • N-(3-oxododecanoyl)homoserine lactone 86%
  • Bacterial Drug Resistance 70%
  • Ligands 69%
  • Antimicrobial Agent 68%
  14 Citationer (Scopus)

• Temporal variability in urinary phthalate metabolite excretion based on spot, morning, and 24-h urine samples: Considerations for epidemiological studies

  Frederiksen, H., Kranich, S. K., Jørgensen, N., Taboureau, O., Petersen, J. H. & Andersson, A. M., 15 jan. 2013, I: Environmental Science & Technology. 47, 2, s. 958-967 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • phthalate 100%
  • Phthalate 95%
  • excretion 91%
  • urine 88%
  • metabolite 77%
  84 Citationer (Scopus)
• 2011

  ChemProt: a disease chemical biology database

  Taboureau, O., Nielsen, S. K., Audouze, K. M. L., Weinhold, N., Edsgärd, D., Roque, F. S., Kouskoumvekaki, I., Bora, A., Curpan, R., Jensen, T. S., Brunak, S. & Oprea, T., jan. 2011, I: Nucleic Acids Research. 39, Database issue, s. D367-72

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chemical Databases 100%
  • Proteins 24%
  • Protein Interaction Maps 23%
  • Molecular Sequence Annotation 12%
  • bisphenol A 12%
  65 Citationer (Scopus)
• 2008

  hERG classification model based on a combination of support vector machine method and GRIND descriptors

  Li, Q., Jørgensen, F. S., Oprea, T., Brunak, S. & Taboureau, O., jan. 2008, I: Molecular Pharmaceutics. 5, 1, s. 117-127 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Support Vector Machine 100%
  • Ether 91%
  • QT Interval 79%
  • Classifier 55%
  • Drug 43%
  65 Citationer (Scopus)