Mikkel Bruhn Schuster

E-mailmikkel.schusterbric.kudk
Webstedhttps://www.bric.ku.dk/research/porse_group/

Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N

Publikationer pr. år

CV

Education

2004 Ph.D., Molecular Biology, University of Copenhagen
1997 M.Sc., Molecular Biology, University of Copenhagen

Career

2008 -
Postdoc, Biotech Research and Innovation Centre

2004 - 2008
Postdoc, Copenhagen University Hospital

2001 - 2004
Ph.D. student, Copenhagen University Hospital/EMBL-Monterotondo

1998 - 2001
Ass. researcher, Copenhagen University Hospital

Primære forskningsområder

C/EBPa in normal hematopoiesis and leukemia

Aktuel forskning

Determinants of the pre-leukemic state in mice with Cebpa mutations
Secondary events in transformation of pre-malignant cells into leukemia
Post-translational regulation of C/EBPa in normal hematopoiesis and leukemia

Interesseområder

Normal and malignant hematopoiesis
HSCs and cancer stem cells

Ekspertise relateret til FN’s Verdensmål

I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:

Fingeraftryk

Dyk ned i forskningsemnerne, hvor Mikkel Bruhn Schuster er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.

9 Lignende profiler

15 Tidsskriftartikel
1 Review

Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes
D'Altri, T., Schuster, M. B., Wenzel, A. & Porse, B. T., 1 okt. 2019, I: European Journal of Haematology. 103, 4, s. 319-328 10 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
2 Citationer (Scopus)
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, M. B., Pundhir, S., Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mönch, K., Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, B. T., 2019, I: Science Advances. 5, 7, s. 1-16 17 s., eaaw4304.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
8 Citationer (Scopus)

9 Downloads (Pure)
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia
Ge, Y., Schuster, M. B., Pundhir, S., Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, B. T., 1 dec. 2019, I: Nature Communications. 10, 1, 14 s., 172.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
7 Citationer (Scopus)

57 Downloads (Pure)
Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors
Pundhir, S., Bratt Lauridsen, F. K., Schuster, M. B., Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P.J.-P., Waage, J., Hasemann, M. S. & Porse, B. T., 29 maj 2018, I: Cell Reports. 23, 9, s. 2744-2757 14 s.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
9 Citationer (Scopus)

56 Downloads (Pure)
The multifaceted functions of C/EBPα in normal and malignant haematopoiesis
Ohlsson, E., Schuster, M. B., Hasemann, M. & Porse, B. T., 1 apr. 2016, I: Leukemia. 30, 4, s. 767-75 9 s.
Publikation: Bidrag til tidsskrift › Review › peer review
29 Citationer (Scopus)
Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq
Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, M. B., Frank, A.-K., Waage, J., Vitting-Seerup, K. & Porse, B. T., 5 feb. 2015, I: BMC Genomics. 16, s. 46
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
19 Citationer (Scopus)

133 Downloads (Pure)
C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors
Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, A.-K., Schuster, M. B., Rapin, N. P.J.-P., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, B. T., jan. 2014, I: P L o S Genetics (Online). 10, 1, s. 1-10 10 s., e1004079.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
58 Citationer (Scopus)

2007 Downloads (Pure)
shRNA screening identifies JMJD1C as being required for leukemia maintenance
Sroczynska, P., Cruickshank, V. A., Bukowski, J.-P., Miyagi, S., Bagger, F. O., Walfridsson, J., Schuster, M. B., Porse, B. & Helin, K., 20 mar. 2014, I: Blood (online).
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
53 Citationer (Scopus)

Mikkel Bruhn Schuster

Personlig profil

CV

Primære forskningsområder

Aktuel forskning

Interesseområder

Ekspertise relateret til FN’s Verdensmål

Fingeraftryk

Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

shRNA screening identifies JMJD1C as being required for leukemia maintenance