Michal Tomasz Marzec

2019

Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling

Ghiasi, S. M., Dahlby, T., Hede Andersen, C., Haataja, L., Petersen, S., Omar-Hmeadi, M., Yang, M., Pihl, C., Bresson, S. E., Khilji, M. S., Klindt, K., Cheta, O., Perone, M. J., Tyrberg, B., Prats, C., Barg, S., Tengholm, A., Arvan, P., Mandrup-Poulsen, T. & Marzec, M. T., 1 apr. 2019, I: Diabetes. 68, 4, s. 747-760 14 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

17 Citationer (Scopus)

MCPIP1 regulates insulin biosynthesis and glucose-stimulated insulin secretion: [Meeting Abstract]

Tyka, K., Brydde, T. H., Wilamowski, M., Jura, J., Marzec, T. & Gurgul-Convey, E., 2019, I: FEBS Open Bio. 9, S1, s. 87-87 P-01-064.

Publikation: Bidrag til tidsskrift › Konferenceartikel › Forskning

2018

Students’ supervision and introduction during the initial period in the research laboratory: does it matter?

Marzec, M. T., 2018, Improving University Science Teaching and Learning: Pedagogical Projects 2018. Department of Science Education, University of Copenhagen, Denmark, s. 107-114 8 s. (Improving University Science Teaching and Learning - Pedagogical Projects, Bind 12).

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

2017

Unexpected profile of sphingolipid contents in blood and bone marrow plasma collected from patients diagnosed with acute myeloid leukemia

WAtek, M., Wollny, T., Pasiarski, M., Gozdz, S., Durnas, B., Wolak, P., Bucki, R., Marzec, M., Chabowska, A. & Zendzian-Piotrowska, M., 8 dec. 2017, I: Lipids in Health and Disease. 16, 1

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

13 Citationer (Scopus)

2016

A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

Marzec, M., Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, O., Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., maj 2016, I: Endocrinology. 157, 5, s. 1914-1928 15 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

4 Citationer (Scopus)

Utility of blood procalcitonin concentration in the management of cancer patients with infections

Durnas, B., Watek, M., Wollny, T., Niemirowicz, K., Marzec, M., Bucki, R. & Gozdz, S., 22 jan. 2016, I: OncoTargets and Therapy. 9, s. 469-475

Publikation: Bidrag til tidsskrift › Review › peer review

17 Citationer (Scopus)

2014

Variation in GRP94 Activity Impacts Production of Igfs and Human Growth

Argon, Y., Grimberg, A., Rosenfeld, R. G. & Marzec, M., 2014, I: Endocrine Reviews. 35, 3

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

2013

Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma.

Lee, S-C., Marzec, M., Liu, X., Wehrli, S., Kantekure, K., Ragunath, P. N., Nelson, D. S., Delikatny, E. J., Glickson, J. D. & Wasik, M. A., jan. 2013, I: NMR in Biomedicine. 26, 1, s. 106-114 9 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

20 Citationer (Scopus)

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming

Marzec, M., Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Andersen, A. W., Zhang, Q., Turner, S. D., Ødum, N. & Wasik, M. A., 15 dec. 2013, I: Journal of immunology (Baltimore, Md. : 1950). 191, 12, s. 6200-7 8 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

13 Citationer (Scopus)

2012

GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum

Marzec, M., Eletto, D. & Argon, Y., mar. 2012, I: B B A - Reviews on Cancer. 1823, 3, s. 774-87 14 s.

Publikation: Bidrag til tidsskrift › Review › peer review

199 Citationer (Scopus)

Prediction and Early Detection of Response by NMR Spectroscopy and Imaging

Lee, S-C., Arias-Mendoza, F., Poptani, H., Delikatny, E. J., Wasik, M., Marzec, M., Schuster, S. J., Nasta, S. D., Svoboda, J., O'Connor, O. A., Smith, M. R. & Glickson, J. D., jan. 2012, I: PET Clinics. 7, 1, s. 119-26 8 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

1 Citationer (Scopus)

2011

Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA

Marzec, M. T., Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Andersen, A. W., Cheng, M., Ødum, N. & Wasik, M. A., 17 mar. 2011, I: Oncogene. 30, 11, s. 1372-1378 7 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

23 Citationer (Scopus)

Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells

Marzec, M. T., Liu, X., Wysocka, M., Rook, A. H., Ødum, N. & Wasik, M. A., 16 sep. 2011, I: PLoS ONE. 6, 9, 8 s., e24849.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

47 Citationer (Scopus)

57 Downloads (Pure)

2010

Plasma gelsolin modulates cellular response to sphingosine 1-phosphate

Bucki, R., Kulakowska, A., Byfield, F. J., Zendzian-Piotrowska, M., Baranowski, M., Marzec, M., Winer, J. P., Ciccarelli, N. J., Gorski, J., Drozdowski, W., Bittman, R. & Janmey, P. A., dec. 2010, I: American Journal of Physiology: Cell Physiology. 299, 6, s. C1516-23

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

43 Citationer (Scopus)

2009

Activation of mTORC1 signaling pathway in AIDS-related lymphomas.

El-Salem, M., Raghunath, P. N., Marzec, M., Liu, X., Kasprzycka, M., Robertson, E. & Wasik, M. A., 2009, I: American Journal of Pathology. 175, 2, s. 817-824 8 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

13 Citationer (Scopus)

Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches

Wasik, M. A., Zhang, Q., Marzec, M., Kasprzycka, M., Wang, H. Y. & Liu, X., 2009, I: Seminars in Oncology. 36, 2 Suppl 1, s. S27-35

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

31 Citationer (Scopus)

2008

Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell lymphoma cells.

Marzec, M., Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, N. F., Rook, A. H. & Wasik, M. A., 2008, I: Cancer Research. 68, 4, s. 1083-91 8 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

64 Citationer (Scopus)

Expression of FOXP3(+) regulatory T-cell phenotype in neoplastic and reactive cells in early mycosis fungoides

Witkiewicz, A. K., Potoczek, M., Kasprzycka, M., Marzec, M. & Wasik, MA., jan. 2008, I: Modern Pathology. 21, s. 103A-103A

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

gamma c-signaling cytokines induce a regulatory T cell phenotype in malignant CD4(+) T lymphocytes

Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Odum, N. & Wasik, M. A., 15 aug. 2008, I: Journal of Immunology. 181, 4, s. 2506-2512

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

Marzec, M., Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, N. & Wasik, M. A., 2008, I: Blood. 111, 4, s. 2181-9 8 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

37 Citationer (Scopus)

Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

Marzec, M., Zhang, Q., Goradia, A., Raghunath, P. N., Liu, X., Paessler, M., Wang, H. Y., Wysocka, M., Cheng, M., Ruggeri, B. A. & Wasik, M. A., 30 dec. 2008, I: Proceedings of the National Academy of Sciences of the United States of America. 105, 52, s. 20852-7 6 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

458 Citationer (Scopus)

γc-Signaling Cytokines Induce a Regulatory T Cell Phenotype in Malignant CD4+ T Lymphocytes.

Kasprzycka, M., Zhang, Q., Witkiewicz, A., Marzec, M., Potoczek, M., Liu, X., Wang, H. Y., Milone, M., Basu, S., Mauger, J., Choi, J. K., Abrams, J. T., Hou, J. S., Rook, A. H., Vonderheid, E., Woetmann, A., Odum, N. & Wasik, M. A., 2008, I: Journal of Immunology. 181, 4, s. 2506-2512 7 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

2007

Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.

El-Salem, M., Raghunath, P. N., Marzec, M., Wlodarski, P., Tsai, D., Hsi, E. & Wasik, M. A., 2007, I: Laboratory Investigation. 87, 1, s. 29-39 11 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

37 Citationer (Scopus)

Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.

Marzec, M., Kasprzycka, M., Liu, X., Raghunath, P. N., Wlodarski, P. & Wasik, M. A., 2007, I: Oncogene. 26, 6, s. 813-821 9 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

65 Citationer (Scopus)

Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec, M., Kasprzycka, M., Liu, X., El-Salem, M., Halasa, K., Raghunath, P. N., Bucki, R., Wlodarski, P. & Wasik, M. A., 2007, I: Oncogene. 26, 38, s. 5606-5614 9 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

77 Citationer (Scopus)

PU.1 activates transcription of SHP-1 gene in hematopoietic cells.

Wlodarski, P., Zhang, Q., Liu, X., Kasprzycka, M., Marzec, M. & Wasik, M. A., 2007, I: Journal of Biological Chemistry. 282, 9, s. 6316-6323 8 s.

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21 Citationer (Scopus)

2006

Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.

Kasprzycka, M., Majewski, M., Wang, Z-J., Ptasznik, A., Wysocka, M., Zhang, Q., Marzec, M., Gimotty, P., Crompton, M. R. & Wasik, M. A., 2006, I: American Journal of Pathology. 168, 5, s. 1631-1641 11 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

31 Citationer (Scopus)

Jak3 contributes to the activation of ALK and Stat3 in ALK + anaplastic large cell lymphoma. Response.

Wasik, M. A. & Marzec, M., 2006, I: Laboratory Investigation. 86, 4, s. 420-421 2 s.

Publikation: Bidrag til tidsskrift › Letter

Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity

Marzec, M., Kasprzycka, M., Lai, R., Gladden, A. B., Wlodarski, P., Tomczak, E., Nowell, P., DePrimo, S. E., Sadis, S., Eck, S., Schuster, S. J., Diehl, J. A. & Wasik, M. A., 1 sep. 2006, I: Blood. 108, 5, s. 1744-1750

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116 Citationer (Scopus)

Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing

Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, M., Gimotty, P., Rook, A. H., Vonderheid, E. C., Odum, N. & Wasik, M. A., 2006, I: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, s. 303-12 9 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

26 Citationer (Scopus)

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

Kasprzycka, M., Marzec, M., Liu, X., Zhang, Q. & Wasik, M. A., 27 jun. 2006, I: Proceedings of the National Academy of Sciences of the United States of America. 103, 26, s. 9964-9969

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120 Citationer (Scopus)

Peroxisome Proliferator-Activated Receptor γ Promotes Lymphocyte Survival through Its Actions on Cellular Metabolic Activities.

Jo, S-H., Yang, C., Miao, Q., Marzec, M., Wasik, M. A., Lu, P. & Wang, Y. L., 2006, I: Journal of Immunology. 177, 6, s. 3737-3745 9 s.

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31 Citationer (Scopus)

2005

Activation of Mammalian Target of Rapamycin in Transformed B Lymphocytes Is Nutrient Dependent but Independent of Akt, Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase, Insulin Growth Factor-I, and Serum.

Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, M., Robertson, E. S., Slupianek, A. & Wasik, M. A., 2005, I: Cancer Research. 65, 17, s. 7800-7808 9 s.

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72 Citationer (Scopus)

Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

Marzec, M., Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, N. & Wasik, M. A., 2005, I: Laboratory Investigation. 85, 12, s. 1544-54 10 s.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

59 Citationer (Scopus)

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang, Q., Wang, H. Y., Marzec, M., Raghunath, P. N., Nagasawa, T. & Wasik, M. A., 2005, I: Proceedings of the National Academy of Sciences of the United States of America. 102, 19, s. 6948-6953 6 s.

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193 Citationer (Scopus)

Michal Tomasz Marzec

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