Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
Dr. Manimozhiyan Arumugam leads the Microbiome Systems Biology research group, investigating how health and diseases are influenced by our gut microbiome; how the gut microbiome interacts with the host and environmental factors; and how we can therapeutically modulate the gut microbiome to improve health. His research is interdisciplinary, combining metagenomics (a technique to study gut microbiome) and other host-microbial multi-omics readouts to study host-microbial cross-talk. He is the principal investigator in several externally funded studies investigating the role of gut microbiome in multiple sclerosis (Lundbeck Foundation), obesity (Novo Nordisk Foundation), liver diseases (EU Horizon 2020), ageing (Danish Independent Research Council) and producing antimicrobial peptides (Danish Independent Research Council).
Dr. Arumugam received his PhD in computational biology from the European Molecular Biology Laboratory (Heidelberg) in 2010.
Masters Thesis Opportunities in Bioinformatics
Highly motivated Masters students are invited to perform their thesis or project work in our group. We prefer students with experience in programming and/or high performance computing. Background in biology is not necessary! Please check out this flyer!
We are always looking for excellent researchers to join our group
| 1. | Postdoctoral fellows in bioinformatics or microbiome research: | |
| Postdoctoral opportunities are available for outstanding candidates with experience and background in bioinformatics and human gut microbiome. If you like our research and are interested in joining our group, please send me an email. | ||
| 2. | PhD fellows in bioinformatics or microbiome research: | |
| We are always looking for highly motivated PhD students to join us. If you like our research and are interested in joining our group, please send me an email. International students can also apply to the Copenhagen Bioscience PhD Program where I am a participating supervisor. | ||
Primære forskningsområder
Human mikrobiom, systembiologi, bioinformatik, metagenomics
Aktuel forskning
Lifestyle changes and lack of physical activity are important factors involved in metabolic disorders. However, emerging evidence suggests that our gut microbiome and their interactions with us play an important role in our health and well-being. An imbalance in the gut microbiome may signify an unhealthy state of the host and contribute to obesity and diabetes pathogenesis.
The Arumugam Group aims to study the interactions between the host and the gut microbiome in order to understand the molecular mechanisms underlying metabolic disorders. The Group takes interdisciplinary approaches combining multi-omics microbiome data to study host-microbial cross-talk. The Group also investigates therapeutic approaches to modulate the gut microbiome towards improving human health.
Interesseområder
Systembiologi, menneskelige sygdomme, genomics, maskinlæring
CV
Education
| May 2010, | Ph.D. Computational Biology | |
| EMBL-Heidelberg, Germany | ||
| Jan 2003, | M.S. Computer Science | |
| Univ. Nebraska-Lincoln, USA | ||
| Jun 1999, | B. Tech. Biotechnology | |
| Anna University, India |
Research Experience
| Feb. 2013 | - | present, | Associate Professor, Group Leader |
| University of Copenhagen, Denmark | |||
| Jun. 2010 | - | July 2012, | Research Scientist |
| EMBL-Heidelberg, Germany | |||
| Sep. 2006 | - | May 2010, | Predoctoral Fellow |
| EMBL-Heidelberg, Germany | |||
| Apr. 2003 | - | Aug. 2006, | Research Associate |
| Washington University in St. Louis, USA |
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Uddannelse (Akademiske kvalifikationer)
Comparative metagenomic analysis of the human gut microbiota, European Molecular Biology Laboratory
1 sep. 2006 → 31 maj 2010
Dimissionsdato: 31 maj 2010
EMPRR: A High-dimensional EM-Based Piecewise Regression Algorithm
10 aug. 2000 → 31 jan. 2003
Dimissionsdato: 16 aug. 2003
Emneord
- Bioinformatik
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Mani Arumugam er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 12 Lignende profiler
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Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S. & Serrano, D. & 15 flere, , 1 apr. 2019, I: Nature Medicine. 25, 4, s. 679-689 11 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J. & Vilsbøll, T. & 4 flere, , 1 nov. 2018, I: Nature Microbiology. 3, 11, s. 1255-1265 11 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Circulating microbiome in blood of different circulatory compartments
Schierwagen, R., Alvarez-Silva, C., Madsen, M. S. A., Kolbe, C. C., Meyer, C., Thomas, D., Uschner, F. E., Magdaleno, F., Jansen, C., Pohlmann, A., Praktiknjo, M., Hischebeth, G. T., Molitor, E., Latz, E., Lelouvier, B., Trebicka, J. & Arumugam, M., 1 mar. 2019, I: Gut. 68, 3, s. 578-580Publikation: Bidrag til tidsskrift › Letter › peer review
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Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, J., Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, B. A. H., Yau, T. O. & Lan, Z. & 19 flere, , 2017, I: Gut. 66, s. 70-78 9 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, T., Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, K. S., Holst, J. J., Madsbad, S., Wang, J., Pedersen, O. B., Hansen, T. & Arumugam, M., 15 jun. 2016, I: Genome Medicine. 8, 13 s., 67.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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A catalog of the mouse gut metagenome
Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D. & Yu, J. & 17 flere, , 1 okt. 2015, I: Nature Biotechnology. 33, 10, s. 1103-1108 6 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Genomic variation landscape of the human gut microbiome
Schloissnig, S., Arumugam, M., Sunagawa, S., Mitreva, M., Tap, J., Zhu, A., Waller, A., Mende, D. R., Kultima, J. R., Martin, J., Kota, K., Sunyaev, S. R., Weinstock, G. M. & Bork, P., 3 jan. 2013, I: Nature. 493, 7430, s. 45-50 6 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum
Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J.-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M. & Kurokawa, K. & 31 flere, , 2011, I: Nature. 473, 7346, s. 174-180 7 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Aktiviteter
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Pharmabiotics Conference 2018
Arumugam, M. (Inviteret foredragsholder)
15 mar. 2018Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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Gut Microbiota for Health World Summit 2018
Arumugam, M. (Inviteret foredragsholder)
10 mar. 2018Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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25th United European Gastroenterology Week
Arumugam, M. (Inviteret foredragsholder)
30 okt. 2017Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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25th United European Gastroenterology Week
Arumugam, M. (Arrangør)
30 okt. 2017Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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53rd Congress of the European Societies of Toxicology
Arumugam, M. (Inviteret foredragsholder)
11 sep. 2017Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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12th Copenhagen Bioscience Conference
Arumugam, M. (Arrangør)
1 okt. 2017 → 5 okt. 2017Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Organisation af og deltagelse i konference
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European Microbiome Congress
Arumugam, M. (Inviteret foredragsholder)
1 dec. 2016Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Deltagelse i workshop, seminar og kursus
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Wenner-Gren Foundation Symposium
Arumugam, M. (Inviteret foredragsholder)
16 jun. 2016Aktivitet: Deltagelse i eller arrangement af en begivenhed - typer › Deltagelse i workshop, seminar og kursus