Jens Bukh

Publikation

Publikationer pr. år 2006 2008 2011 2013 2014 2018 2019 2019

• 116 Tidsskriftartikel
• 10 Patent
• 4 Bidrag til bog/antologi
• 4 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2011

  Non-genotype-specific role of the hepatitis C virus 5' untranslated region in virus production and in inhibition by interferon

  Li, Y-P., Ramirez, S., Gottwein, J. M. & Bukh, J., 20 dec. 2011, I: Virology: Research and Treatment. 421, 2, s. 222-34 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 5' Untranslated Regions 100%
  • Hepacivirus 79%
  • Interferons 79%
  • Viruses 57%
  • Genotype 47%
  19 Citationer (Scopus)

• Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-a

  Scheel, T. K. H., Gottwein, J. M., Mikkelsen, L. S., Jensen, T. B. & Bukh, J., mar. 2011, I: Gastroenterology Today. 140, 3, s. 1032-42 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepacivirus 100%
  • Interferons 99%
  • Genotype 77%
  • BMS-790052 62%
  • Mutation 30%
  119 Citationer (Scopus)

• The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae

  Stapleton, J. T., Foung, S., Muerhoff, A. S., Bukh, J. & Simmonds, P., feb. 2011, I: Journal of General Virology. 92, Pt 2, s. 233-46 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GB virus A 100%
  • GB virus C 73%
  • Flaviviridae 72%
  • Hepatitis 33%
  • Viruses 32%
  192 Citationer (Scopus)

• Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8¿ T cells in early viral evolution

  Callendret, B., Bukh, J., Eccleston, H. B., Heksch, R., Hasselschwert, D. L., Purcell, R. H., Hughes, A. L. & Walker, C. M., nov. 2011, I: Journal of Virology. 85, 22, s. 11833-45 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C virus 100%
  • Hepacivirus 63%
  • T-lymphocytes 62%
  • Genome 46%
  • T-Lymphocytes 42%
  24 Citationer (Scopus)

• Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus

  Meunier, J-C., Gottwein, J. M., Houghton, M., Russell, R. S., Emerson, S. U., Bukh, J. & Purcell, R. H., 15 okt. 2011, I: Journal of Infectious Diseases. 204, 8, s. 1186-90 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Neutralizing Antibodies 100%
  • Hepacivirus 92%
  • Vaccines 74%
  • Genotype 71%
  • Pan troglodytes 49%
  77 Citationer (Scopus)
• 2010

  Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models

  Bukh, J., Meuleman, P., Tellier, R., Engle, R. E., Feinstone, S. M., Eder, G., Satterfield, W. C., Govindarajan, S., Krawczynski, K., Miller, R. H., Leroux-Roels, G. & Purcell, R. H., 1 maj 2010, I: Journal of Infectious Diseases. 201, 9, s. 1381-9 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Pan troglodytes 100%
  • Hepacivirus 74%
  • Virulence 70%
  • Genotype 57%
  • Liver 41%
  60 Citationer (Scopus)

• Molecular and epidemiological profiles of hepatitis C virus genotype 4 in Denmark

  Eriksen, M. B., Jørgensen, L. B., Krarup, H., Laursen, A. L., Christensen, P. B., Møller, A., Schlichting, P., Kuiken, C., Bukh, J., Weis, N. & DANHEP Group, nov. 2010, I: Journal of Medical Virology. 82, 11, s. 1869-1877 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Denmark 100%
  • Hepacivirus 87%
  • Genotype 67%
  • Southern Africa 10%
  • Northern Africa 9%
  9 Citationer (Scopus)

• Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins

  Takikawa, S., Engle, R. E., Faulk, K. N., Emerson, S. U., Purcell, R. H. & Bukh, J., 2010, I: Journal of General Virology. 91, Pt 3, s. 727-33 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GB virus B 100%
  • Cercopithecine Herpesvirus 1 72%
  • Molecular Evolution 68%
  • Hepatitis Viruses 67%
  • Infections 25%
  19 Citationer (Scopus)

• Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies

  Bidragets oversatte titel: Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studiesGottwein, J., Scheel, T., Callendret, B., Li, Y., Eccleston, H. B., Engle, R. E., Govindarajan, S., Satterfield, W., Purcell, R. H., Walker, C. M. & Bukh, J., maj 2010, I: Journal of Virology. 84, 10, s. 5277-93 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C virus 100%
  • Hepacivirus 63%
  • pathogenesis 62%
  • Complementary DNA 55%
  • Clone Cells 54%
  100 Citationer (Scopus)
• 2009

  DELETION OF HYPERVARIABLE REGION 1 (HVR1) OF E2 FROM HCV GENOTYPES 1-6 HAS DIFFERENTIAL EFFECT ON INFECTIVITY IN VITRO AND CAUSES INCREASED SUSCEPTIBILITY TO NEUTRALIZATION

  Prentoe, J., Gottwein, J. M., Scheel, T. K. H., Jensen, T. B., Serre, S. & Bukh, J., 2009, I: Journal of Hepatology. 50, s. S34-S34

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: role of CD81 and scavenger receptor class B type I and effect of antiviral drugs

  Gottwein, J. M., Scheel, T. K. H., Jensen, T. B., Lademann, J. B., Prentoe, J. C., Knudsen, M. L., Hoegh, A. M. & Bukh, J., 2009, I: Hepatology. 49, 2, s. 364-77 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • CD36 Antigens 100%
  • Hepacivirus 64%
  • Antiviral Agents 59%
  • Cell Culture Techniques 52%
  • Genotype 49%
  281 Citationer (Scopus)

• MONOCISTRONIC HEPATITIS C REPORTER VIRUS RECOMBINANTS OF ALL MAJOR GENOTYPES EXPRESSING ENHANCED GREEN FLUORESCENT PROTEIN TAGGED NS5A PROTEIN

  Gottwein, J. M., Lademann, J. B., Scheel, T. K. H., Jensen, T. B., Prentoe, J. C. & Bukh, J., 2009, I: Journal of Hepatology. 50, s. S33-S33

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles

  Russell, R. S., Kawaguchi, K., Meunier, J-C., Takikawa, S., Faulk, K., Bukh, J., Purcell, R. H. & Emerson, S. U., 2009, I: Journal of Viral Hepatitis. 16, 9, s. 621-32 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C virus E1 protein 100%
  • Virion 53%
  • Cell Culture Techniques 42%
  • Hepacivirus 41%
  • Peptides 35%
  28 Citationer (Scopus)

• Predictors of antiviral treatment initiation in hepatitis C virus-infected patients: a Danish cohort study

  Hansen, N., Obel, N., Christensen, P. B., Krarup, H., Laursen, A. L., Clausen, M. R., Lunding, S., Møller, A., Schlichting, P., Kromann-Andersen, H., Bukh, J., Weis, N., Hansen, N., Obel, N., Christensen, P. B., Krarup, H., Laursen, A. L., Clausen, M. R., Lunding, S., Møller, A., & 4 flereSchlichting, P., Kromann-Andersen, H., Bukh, J. & Weis, N. M., 2009, I: Journal of Viral Hepatitis. 16, 9, s. 659-65 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepacivirus 100%
  • Antiviral Agents 92%
  • Cohort Studies 73%
  • Peptide Initiation Factors 61%
  • Confidence Intervals 35%
  24 Citationer (Scopus)
• 2008

  Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

  Russell, R. S., Meunier, J-C., Takikawa, S., Faulk, K., Engle, R. E., Bukh, J., Purcell, R. H. & Emerson, S. U., 18 mar. 2008, I: PNAS Early Edition. 105, 11, s. 4370-5 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepacivirus 100%
  • Cell Culture Techniques 82%
  • Mutation 60%
  • Viruses 44%
  • Serial Passage 18%
  138 Citationer (Scopus)

• Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems.

  Gottwein, J. M. & Bukh, J., 2008, I: Advances in Virus Research. 71, s. 51-133 82 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Life Cycle Stages 100%
  • Hepacivirus 86%
  • Cell Culture Techniques 70%
  • Genotype 39%
  • Virion 35%
  83 Citationer (Scopus)

• Development of a TaqMan assay for the six major genotypes of hepatitis C virus: Comparison with commercial assays

  Engle, R. E., Russell, R. S., Purcell, R. H. & Bukh, J., 2008, I: Journal of Medical Virology. 80, 1, s. 72-9 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepacivirus 100%
  • Genotype 77%
  • RNA 33%
  • Technology 12%
  • Nucleic Acids 9%
  21 Citationer (Scopus)

• Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

  Scheel, T. K. H., Gottwein, J. M., Jensen, T. B., Prentø, J. C., Høegh, A. M., Alter, H. J., Eugen-Olsen, J. & Bukh, J., 2008, I: Proceedings of the National Academy of Science of the United States of America. 105, 3, s. 997-1002 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  149 Citationer (Scopus)

• Hepatitis C: the virus and studies of its lifecycle in cell culture systems

  Bukh, J., Gottwein, J. M., Scheel, T. K. & Forns, X., 2008, 100 Key Questions on Hepatitis C. Forns, X. (red.). 1 udg. Barcelona, Spain: Permanyer Publications, Bind 1. s. 1-15 14 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

• Highly Efficient JFH1-Based Cell-Culture System for Hepatitis C Virus Genotype 5a: Failure of Homologous Neutralizing-Antibody Treatment to Control Infection

  Jensen, T. B., Gottwein, J. M., Scheel, T. K. H., Høgh, A. M., Eugen-Olsen, J. & Bukh, J., 2008, I: Journal of Infectious Diseases. 198, 12, s. 1756-1765 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Infection Control 100%
  • Neutralizing Antibodies 98%
  • Hepacivirus 91%
  • Cell Culture Techniques 75%
  • Genotype 70%
  87 Citationer (Scopus)

• Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived

  Bukh, J., Engle, R. E., Govindarajan, S. & Purcell, R. H., 2008, I: Journal of Medical Virology. 80, 1, s. 87-94 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GB virus B 100%
  • Cercopithecine Herpesvirus 1 72%
  • Hepatitis Viruses 67%
  • Immunity 43%
  • Viremia 40%
  13 Citationer (Scopus)

• Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death.

  Mateu, G., Donis, R. O., Wakita, T., Bukh, J. & Grakoui, A., 2008, I: Virology. 376, 2, s. 397-407 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  45 Citationer (Scopus)

• Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus

  Meunier, J-C., Russell, R. S., Goossens, V., Priem, S., Walther, H., Depla, E., Union, A., Faulk, K. N., Bukh, J., Emerson, S. U. & Purcell, R. E., 2008, I: Journal of Virology. 82, 2, s. 966-73 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C virus E1 protein 100%
  • Hepatitis C virus 80%
  • neutralization 57%
  • Hepacivirus 51%
  • monoclonal antibodies 49%
  126 Citationer (Scopus)

• Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain.

  Vanwolleghem, T., Bukh, J., Meuleman, P., Desombere, I., Meunier, J-C., Alter, H., Purcell, R. H. & Leroux-Roels, G., 2008, I: Hepatology. 47, 6, s. 1846-1855 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chronic Hepatitis C 100%
  • Hepacivirus 88%
  • Immunoglobulins 84%
  • Immunoglobulin G 72%
  • Liver 49%
  110 Citationer (Scopus)

• Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.

  Bukh, J., Thimme, R., Meunier, J-C., Faulk, K., Spangenberg, H. C., Chang, K-M., Satterfield, W., Chisari, F. V. & Purcell, R. H., 2008, I: Journal of Virology. 82, 16, s. 8183-95 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C virus 100%
  • Pan troglodytes 85%
  • Hepacivirus 63%
  • Viruses 45%
  • viruses 37%
  74 Citationer (Scopus)
• 2007

  Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

  Mikkelsen, M. & Bukh, J., 2007, I: Current Infectious Disease Reports. 9, 2, s. 94-101 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C 100%
  • Hepacivirus 90%
  • Vaccines 73%
  • Virus Diseases 23%
  • Genotype 23%
  18 Citationer (Scopus)

• Hepatitis C virus host cell interactions uncovered

  Gottwein, J. & Bukh, J., 2007, I: Proceedings of the National Academy of Science of the United States of America. 104, 33, s. 13215-6

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Host Microbial Interactions 100%
  • Cell Communication 74%
  • Hepacivirus 74%
  • Life Cycle Stages 19%
  • Antiviral Agents 15%
  4 Citationer (Scopus)

• In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells

  Sakai, A., Takikawa, S., Thimme, R., Meunier, J. C., Spangenberg, H. C., Govindarajan, S., Farci, P., Emerson, S. U., Chisari, F. V., Purcell, R. H. & Bukh, J., 2007, I: Journal of Virology. 81, 13, s. 7208-7219 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  45 Citationer (Scopus)

• Monitoring of hepatitis C virus quasispecies in chronic infection by matrix-assisted laser desorption ionization-time of flight mass spectrometry mutation detection

  Yea, C., Bukh, J., Ayers, M., Roberts, E., Krajden, M. & Tellier, R., 2007, I: Journal of Clinical Microbiology. 45, 3, s. 1053-1057 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  8 Citationer (Scopus)

• Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses

  Gottwein, J. M., Scheel, T. K. H., Hoegh, A. M., Lademann, J. B., Eugen-Olsen, J., Lisby, G. & Bukh, J., 2007, I: Gastroenterology. 133, 5, s. 1614-26 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatitis C 100%
  • Hepacivirus 90%
  • Cell Culture Techniques 74%
  • Genotype 69%
  • Viruses 65%
  154 Citationer (Scopus)
• 2006

  A comprehensive system for consistent numbering of HCV sequences, proteins and epitopes.

  Kuiken, C., Combet, C., Bukh, J., Shin-I, T., Deleage, G., Mizokami, M., Richardson, R., Sablon, E., Yusim, K., Pawlotsky, J-M., Simmonds, P. & Los Alamos HIV Database Group, 2006, I: Hepatology. 44, 5, s. 1355-61 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  86 Citationer (Scopus)

• A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo.

  Bukh, J. & Purcell, R. H., 2006, I: Proceedings of the National Academy of Sciences of the United States of America. 103, 10, s. 3500-1 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  23 Citationer (Scopus)

• Functional analyses of GB virus B p13 protein: Development of a recombinant GB virus B hepatitis virus with a p7 protein

  Takikawa, S., Engle, R. E., Emerson, S. U., Purcell, R. H., St Claire, M. & Bukh, J., 2006, I: Proceedings of the National Academy of Science of the United States of America. 103, 9, s. 3345-50 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • GB virus B 100%
  • Cercopithecine Herpesvirus 1 72%
  • Hepatitis Viruses 67%
  • Amino Acids 37%
  • Hepacivirus 29%
  27 Citationer (Scopus)

• Hepatitis C hos hiv-inficerede patienter

  Bukh, J. & Nielsen, J. O., 2006, I: Ugeskrift for læger. 168, 42, s. 3599-

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review