Publikationer pr. år
Publikationer pr. år
Personlig profil
CV
Jacob B. Hansen, Ph.D.
Jacob B. Hansen joined the Faculty of Health Sciences in February 2005. Before that he carried out 3-4 years of postdoctoral training at the Netherlands Cancer Institute in Amsterdam working mainly on directed differentiation of gene-targeted embryonic stem cells. Jacob obtained his Ph.D. in molecular biology from the University of Southern Denmark in 2001. His Ph.D. project dealt with functions of peroxisome proliferator-activated receptors and the retinoblastoma protein in fat cell (adipocyte) differentiation. His work at the Department of Biomedical Sciences focuses on identification of novel molecular determinants regulating white versus brown adipocyte differentiation as well as factors contributing to mitochondrial respiration and biogenesis during adipose conversion.
Education and employment
May 2011-present
Associate professor at the Department of Biomedical Sciences, the Panum Institute, University of Copenhagen.
February 2007-April 2011
Assistant professor at the Department of Biomedical Sciences, the Panum Institute, University of Copenhagen.
February 2005-January 2007
Research assistant professor in the Diabetes and Stem Cell Group at the Department of Medical Biochemistry and Genetics, the Panum Institute, University of Copenhagen.
Supported by the Carlsberg Foundation.
November 2004-January 2005:
Research assistant professor at the Department of Biochemistry and Molecular Biology, University of Southern Denmark.
April 2001-September 2004:
Postdoctoral fellow at the Netherlands Cancer Institute, Amsterdam.
Supervisor: Hein te Riele, professor, Ph.D., head of division.
Supported by fellowships from the Federation of European Biochemical Societies and the Dutch Cancer Society.
October 1996-March 2001:
Ph.D. studies at the Department of Biochemistry and Molecular Biology, University of Southern Denmark.
Supervisor: Karsten Kristiansen, professor.
Title of Ph.D. thesis: Regulation of adipogenesis by the retinoblastoma protein and peroxisome proliferator-activated receptors. Ph.D. awarded in March 2001.
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Emneord
- Det Sundhedsvidenskabelige Fakultet
- Molekylær Biologi
- Cellebiologi
- Cellulær differentiering
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Jacob B. Hansen er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 6 Lignende profiler
Publikation
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Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration
Tozzi, M., Hansen, J. B. & Novak, I., 1 feb. 2020, I: Acta Physiologica. 18 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice
Danneskiold-Samsøe, N. B., Sonne, S. B., Larsen, J. M., Hansen, A. N., Fjære, E., Isidor, M. S., Petersen, S., Henningsen, J., Severi, I., Sartini, L., Schobers, Y., Wolf, J., Nockhers, W. A., Wolfrum, C., Cinti, S., Sina, C., Hansen, J. B., Madsen, L., Brix, S. & Kristiansen, K., 1 dec. 2019, I: Scientific Reports. 9, 13 s., 8979.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome
Mortensen, L. J., Lorenzen, M., Jørgensen, N., Andersson, A-M., Nielsen, J. E., Petersen, L. I., Lanske, B., Juul, A., Hansen, J. B. & Jensen, M. B., jun. 2019, I: Bone. 123, s. 103-114Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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GSK3 is a negative regulator of the thermogenic program in brown adipocytes
Markussen, L. K., Winther, S., Wicksteed, B. & Hansen, J. B., 1 dec. 2018, I: Scientific Reports. 8, s. 1-12 3469.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro
Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, J. B., Pedersen, S. B., Richelsen, B. & Jessen, N., sep. 2018, I: Diabetes, Obesity and Metabolism. 20, 9, s. 2264-2273Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption
Winther, S., Isidor, M. S., Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, J. B., mar. 2018, I: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, s. E214-E223 10 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor
Markussen, L. K., Isidor, M. S., Breining, P., Andersen, E. S., Rasmussen, N. E., Petersen, L. I., Pedersen, S. B., Richelsen, B. & Hansen, J. B., 28 sep. 2017, I: PLoS ONE. 12, 9, 17 s., e0185624.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism
Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, M. S., Markussen, L. K., Viuff, B. M., Lambert, I. H., Hansen, J. B. & Pedersen, S. H. F., 12 okt. 2017, I: Scientific Reports. 7, 1, 13 s., 13101.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review