Women with Stable Angina Pectoris and No Obstructive Coronary Artery Disease: Closer to a Diagnosis

Marie Mide Michelsen; Naja Dam Mygind; Daria Frestad; Eva Prescott

doi:10.15420/ecr.2016:33:2

Women with Stable Angina Pectoris and No Obstructive Coronary Artery Disease: Closer to a Diagnosis

Marie Mide Michelsen^*, Naja Dam Mygind, Daria Frestad, Eva Prescott

^*Corresponding author for this work

Department of Clinical Medicine

6 Citations (Scopus)

Abstract

A large proportion of women with chest pain have no obstructive coronary artery disease. Recent studies have demonstrated that these women continue to have symptoms and are at increased risk of cardiovascular morbidity and mortality. Coronary microvascular dysfunction (CMD) leads to an impairment of blood flow regulation to the myocardium and possible transient ischaemia. CMD is a disease entity with several pathophysiologic aspects and diagnostic modalities continue to be developed. However, due to the complexity of the disease, it remains elusive whether CMD is the explanation for the symptoms and the poor prognosis in women with angina and no obstructive coronary artery disease.

Original language	English
Journal	European Cardiology Review
Volume	12
Issue number	1
Pages (from-to)	14-19
Number of pages	6
ISSN	1758-3756
DOIs	https://doi.org/10.15420/ecr.2016:33:2
Publication status	Published - Jan 2017

Keywords

Coronary microvascular disease
Diagnosis
Imaging
Ischaemia
Myocardium
No obstructive coronary artery disease
Stable angina pectoris
Women

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https://www.ecrjournal.com/system/files/articles/ECR12_1-16-21.pdf

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title = "Women with Stable Angina Pectoris and No Obstructive Coronary Artery Disease: Closer to a Diagnosis",

abstract = "A large proportion of women with chest pain have no obstructive coronary artery disease. Recent studies have demonstrated that these women continue to have symptoms and are at increased risk of cardiovascular morbidity and mortality. Coronary microvascular dysfunction (CMD) leads to an impairment of blood flow regulation to the myocardium and possible transient ischaemia. CMD is a disease entity with several pathophysiologic aspects and diagnostic modalities continue to be developed. However, due to the complexity of the disease, it remains elusive whether CMD is the explanation for the symptoms and the poor prognosis in women with angina and no obstructive coronary artery disease.",

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AU - Michelsen, Marie Mide

AU - Mygind, Naja Dam

AU - Frestad, Daria

AU - Prescott, Eva

PY - 2017/1

Y1 - 2017/1

N2 - A large proportion of women with chest pain have no obstructive coronary artery disease. Recent studies have demonstrated that these women continue to have symptoms and are at increased risk of cardiovascular morbidity and mortality. Coronary microvascular dysfunction (CMD) leads to an impairment of blood flow regulation to the myocardium and possible transient ischaemia. CMD is a disease entity with several pathophysiologic aspects and diagnostic modalities continue to be developed. However, due to the complexity of the disease, it remains elusive whether CMD is the explanation for the symptoms and the poor prognosis in women with angina and no obstructive coronary artery disease.

AB - A large proportion of women with chest pain have no obstructive coronary artery disease. Recent studies have demonstrated that these women continue to have symptoms and are at increased risk of cardiovascular morbidity and mortality. Coronary microvascular dysfunction (CMD) leads to an impairment of blood flow regulation to the myocardium and possible transient ischaemia. CMD is a disease entity with several pathophysiologic aspects and diagnostic modalities continue to be developed. However, due to the complexity of the disease, it remains elusive whether CMD is the explanation for the symptoms and the poor prognosis in women with angina and no obstructive coronary artery disease.

KW - Coronary microvascular disease

KW - Diagnosis

KW - Imaging

KW - Ischaemia

KW - Myocardium

KW - No obstructive coronary artery disease

KW - Stable angina pectoris

KW - Women

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DO - 10.15420/ecr.2016:33:2

M3 - Journal article

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EP - 19

JO - European Cardiology

JF - European Cardiology

IS - 1

ER -

Women with Stable Angina Pectoris and No Obstructive Coronary Artery Disease: Closer to a Diagnosis

Abstract

Keywords

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