TY - JOUR
T1 - Women with inoperable or locally advanced breast cancer -- what characterizes them?
T2 - A retrospective review of 157 cases
AU - El-Charnoubi, Waseem Asim Ghulam
AU - Svendsen, Jesper Brink
AU - Tange, Ulla Brix
AU - Kroman, Niels
PY - 2012/11
Y1 - 2012/11
N2 - Background. Breast cancer is the most common cancer among Danish women. Locally advanced breast cancer occurs in a relatively large proportion of all new primary breast cancer diagnoses and for unexplained reasons 2030% of women with breast cancer wait more than eight weeks from the initial breast cancer symptom(s) before seeking medical advice. Material and methods. In this study, we performed a retrospective review of the medical records of patients referred to The Department of Breast Surgery, Rigshospitalet in Copenhagen in the period between 2006 and 2011, to characterize women presenting with breast cancer either larger than 5 cm or locally advanced breast cancer/inoperable breast cancer (LABC/IOBC). The aim of the study was to characterize these women concerning age, social status, co-morbidity, defined anamnestic parameters concerning breast history and delay in seeking medical advice, to explore whether common traits among these parameters could be identified which could account for the late diagnosis. Results. We identified 157 cases. The median age of our cohort was 67 years (range 3098) and did not differ from all women with breast cancer, but with a high risk of severe medical co-morbidity, psychiatric co-morbidity or dementia. However, 42% did not reveal any history of a psychiatric or somatic co-morbidity did not take psychoactive drugs and had no previous benign breast disorder. They were living in their own homes, were married, did not suffer from dementia, could have a first-degree relative with a history of breast cancer, but still presented with breast cancer characterized as LABC/IOBC, without any apparent reason. Among these 42%, more than half had neglected their obvious symptoms of breast cancer.
AB - Background. Breast cancer is the most common cancer among Danish women. Locally advanced breast cancer occurs in a relatively large proportion of all new primary breast cancer diagnoses and for unexplained reasons 2030% of women with breast cancer wait more than eight weeks from the initial breast cancer symptom(s) before seeking medical advice. Material and methods. In this study, we performed a retrospective review of the medical records of patients referred to The Department of Breast Surgery, Rigshospitalet in Copenhagen in the period between 2006 and 2011, to characterize women presenting with breast cancer either larger than 5 cm or locally advanced breast cancer/inoperable breast cancer (LABC/IOBC). The aim of the study was to characterize these women concerning age, social status, co-morbidity, defined anamnestic parameters concerning breast history and delay in seeking medical advice, to explore whether common traits among these parameters could be identified which could account for the late diagnosis. Results. We identified 157 cases. The median age of our cohort was 67 years (range 3098) and did not differ from all women with breast cancer, but with a high risk of severe medical co-morbidity, psychiatric co-morbidity or dementia. However, 42% did not reveal any history of a psychiatric or somatic co-morbidity did not take psychoactive drugs and had no previous benign breast disorder. They were living in their own homes, were married, did not suffer from dementia, could have a first-degree relative with a history of breast cancer, but still presented with breast cancer characterized as LABC/IOBC, without any apparent reason. Among these 42%, more than half had neglected their obvious symptoms of breast cancer.
U2 - 10.3109/0284186x.2012.707788
DO - 10.3109/0284186x.2012.707788
M3 - Journal article
C2 - 22909390
SN - 0284-186X
VL - 51
SP - 1081
EP - 1085
JO - Acta Oncologica
JF - Acta Oncologica
IS - 8
ER -
