Weight preserving image registration for monitoring disease progression in lung CT.

Vladlena Gorbunova; Pechin Chien Pau Lo; Ashraf Haseem; Asger Dirksen; Mads Nielsen; Marleen de Bruijne

doi:10.1007/978-3-540-85990-1_104

Weight preserving image registration for monitoring disease progression in lung CT.

Vladlena Gorbunova, Pechin Chien Pau Lo, Ashraf Haseem, Asger Dirksen, Mads Nielsen, Marleen de Bruijne

Department of Computer Science

34 Citations (Scopus)

Abstract

We present a new image registration based method for monitoring regional disease progression in longitudinal image studies of lung disease. A free-form image registration technique is used to match a baseline 3D CT lung scan onto a following scan. Areas with lower intensity in the following scan compared with intensities in the deformed baseline image indicate local loss of lung tissue that is associated with progression of emphysema. To account for differences in lung intensity owing to differences in the inspiration level in the two scans rather than disease progression, we propose to adjust the density of lung tissue with respect to local expansion or compression such that the total weight of the lungs is preserved during deformation. Our method provides a good estimation of regional destruction of lung tissue for subjects with a significant difference in inspiration level between CT scans and may result in a more sensitive measure of disease progression than standard quantitative CT measures.

Original language	English
Title of host publication	Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008 : 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II
Editors	D. Metaxas, L. Axel, G. Fichtinger, G. Szekely
Number of pages	8
Publisher	Springer
Publication date	2008
Pages	863-871
ISBN (Print)	978-3-540-85989-5
DOIs	https://doi.org/10.1007/978-3-540-85990-1_104
Publication status	Published - 2008
Event	International Conference on Medical Image Computing and Computer-Assisted Intervention - New York, NY, United States Duration: 6 Sept 2008 → 10 Sept 2008 Conference number: 11

Conference

Conference	International Conference on Medical Image Computing and Computer-Assisted Intervention
Number	11
Country/Territory	United States
City	New York, NY
Period	06/09/2008 → 10/09/2008

Series	Lecture notes in computer science
Number	5242
ISSN	0302-9743

Access to Document

10.1007/978-3-540-85990-1_104

Cite this

Gorbunova, V., Lo, P. C. P., Haseem, A., Dirksen, A., Nielsen, M., & de Bruijne, M. (2008). Weight preserving image registration for monitoring disease progression in lung CT. In D. Metaxas, L. Axel, G. Fichtinger, & G. Szekely (Eds.), Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008: 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II (pp. 863-871). Springer. Lecture notes in computer science No. 5242 https://doi.org/10.1007/978-3-540-85990-1_104

Weight preserving image registration for monitoring disease progression in lung CT. / Gorbunova, Vladlena; Lo, Pechin Chien Pau; Haseem, Ashraf et al.

Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008: 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II. ed. / D. Metaxas; L. Axel; G. Fichtinger; G. Szekely. Springer, 2008. p. 863-871 (Lecture notes in computer science; No. 5242).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Gorbunova, V, Lo, PCP, Haseem, A, Dirksen, A, Nielsen, M & de Bruijne, M 2008, Weight preserving image registration for monitoring disease progression in lung CT. in D Metaxas, L Axel, G Fichtinger & G Szekely (eds), Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008: 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II. Springer, Lecture notes in computer science, no. 5242, pp. 863-871, International Conference on Medical Image Computing and Computer-Assisted Intervention, New York, NY, United States, 06/09/2008. https://doi.org/10.1007/978-3-540-85990-1_104

Gorbunova V, Lo PCP, Haseem A, Dirksen A, Nielsen M , de Bruijne M. Weight preserving image registration for monitoring disease progression in lung CT. In Metaxas D, Axel L, Fichtinger G, Szekely G, editors, Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008: 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II. Springer. 2008. p. 863-871. (Lecture notes in computer science; No. 5242). doi: 10.1007/978-3-540-85990-1_104

Gorbunova, Vladlena ; Lo, Pechin Chien Pau ; Haseem, Ashraf et al. / Weight preserving image registration for monitoring disease progression in lung CT. Mecical Image Computing and Computer-Assisted Intervention - MICCAI 2008: 11th International Conference, New York, NY, USA, September 6-10, 2008, proceedings, Part II. editor / D. Metaxas ; L. Axel ; G. Fichtinger ; G. Szekely. Springer, 2008. pp. 863-871 (Lecture notes in computer science; No. 5242).

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