Vitamin D receptor and estrogen receptor gene polymorphisms in postmenopausal Danish women: no relation to bone markers or serum lipoproteins

Y Z Bagger, C Hassager, Anne-Marie Heegaard, C Christiansen

13 Citations (Scopus)

Abstract

To investigate the polymorphisms of the vitamin D receptor (VDR) and estrogen receptor (ER) genes in relation to biochemical markers of bone turnover (serum osteocalcin and urinary collagen type I degradation products (CrossLaps), and to study ER genotypes in relation to serum lipoproteins, blood pressure, or changes in these parameters after 2 years of hormone replacement therapy (HRT) in 499 Danish postmenopausal women.
Original languageEnglish
JournalClimacteric
Volume3
Issue number2
Pages (from-to)84-91
Number of pages8
ISSN1369-7137
Publication statusPublished - 2000

Keywords

  • Aged
  • Bone and Bones
  • Collagen
  • Collagen Type I
  • Denmark
  • Deoxyribonucleases, Type II Site-Specific
  • Estrogen Replacement Therapy
  • Female
  • Genotype
  • Humans
  • Imidoesters
  • Lipoproteins
  • Middle Aged
  • Osteocalcin
  • Peptides
  • Polymorphism, Restriction Fragment Length
  • Postmenopause
  • Receptors, Calcitriol
  • Receptors, Estrogen
  • Regression Analysis

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