Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016

Linda A Rasch; Maarten Boers; Catherine L Hill; Marieke Voshaar; Wijnanda Hoogland; Maarten de Wit; Caroline Flurey; Bev Davis; Merete Lund Hetland; Cecilie Heegaard Brahe; Laure Gossec; George A Wells; Peter Tugwell; Bindee Kuriya; Niti Goel; Jasvinder A Singh; Cátia Duarte; José Da Silva; Dirkjan van Schaardenburg; Susanna Proudman; Lilian H D van Tuyl; Working Group on the Patients’ Perspective on Remission in Rheumatoid Arthritis

doi:10.3899/jrheum.161111

Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016

Linda A Rasch, Maarten Boers, Catherine L Hill, Marieke Voshaar, Wijnanda Hoogland, Maarten de Wit, Caroline Flurey, Bev Davis, Merete Lund Hetland, Cecilie Heegaard Brahe, Laure Gossec, George A Wells, Peter Tugwell, Bindee Kuriya, Niti Goel, Jasvinder A Singh, Cátia Duarte, José Da Silva, Dirkjan van Schaardenburg, Susanna ProudmanLilian H D van Tuyl, Working Group on the Patients’ Perspective on Remission in Rheumatoid Arthritis

Department of Clinical Medicine

5 Citations (Scopus)

Abstract

OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.

METHODS: A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.

RESULTS: At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO.

CONCLUSION: More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.

Original language	English
Journal	Journal of Rheumatology
Volume	44
Issue number	12
Pages (from-to)	1889-1893
ISSN	0315-162X
DOIs	https://doi.org/10.3899/jrheum.161111
Publication status	Published - 1 Dec 2017

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Rasch, L. A., Boers, M., Hill, C. L., Voshaar, M., Hoogland, W., de Wit, M., Flurey, C., Davis, B., Hetland, M. L., Brahe, C. H., Gossec, L., Wells, G. A., Tugwell, P., Kuriya, B., Goel, N., Singh, J. A., Duarte, C., Da Silva, J., van Schaardenburg, D., ... Working Group on the Patients’ Perspective on Remission in Rheumatoid Arthritis (2017). Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016. Journal of Rheumatology, 44(12), 1889-1893. https://doi.org/10.3899/jrheum.161111

Rasch, LA, Boers, M, Hill, CL, Voshaar, M, Hoogland, W, de Wit, M, Flurey, C, Davis, B, Hetland, ML, Brahe, CH, Gossec, L, Wells, GA, Tugwell, P, Kuriya, B, Goel, N, Singh, JA, Duarte, C, Da Silva, J, van Schaardenburg, D, Proudman, S, van Tuyl, LHD & Working Group on the Patients’ Perspective on Remission in Rheumatoid Arthritis 2017, 'Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016', Journal of Rheumatology, vol. 44, no. 12, pp. 1889-1893. https://doi.org/10.3899/jrheum.161111

@article{33a275b3ce594a3da9c661214ad553e7,

title = "Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016",

abstract = "OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.METHODS: A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.RESULTS: At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO.CONCLUSION: More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.",

author = "Rasch, {Linda A} and Maarten Boers and Hill, {Catherine L} and Marieke Voshaar and Wijnanda Hoogland and {de Wit}, Maarten and Caroline Flurey and Bev Davis and Hetland, {Merete Lund} and Brahe, {Cecilie Heegaard} and Laure Gossec and Wells, {George A} and Peter Tugwell and Bindee Kuriya and Niti Goel and Singh, {Jasvinder A} and C{\'a}tia Duarte and {Da Silva}, Jos{\'e} and {van Schaardenburg}, Dirkjan and Susanna Proudman and {van Tuyl}, {Lilian H D} and {Working Group on the Patients{\textquoteright} Perspective on Remission in Rheumatoid Arthritis}",

year = "2017",

month = dec,

day = "1",

doi = "10.3899/jrheum.161111",

language = "English",

volume = "44",

pages = "1889--1893",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology Publishing Co. Ltd.",

number = "12",

}

TY - JOUR

T1 - Validating Rheumatoid Arthritis Remission Using the Patients' Perspective

T2 - Results from a Special Interest Group at OMERACT 2016

AU - Rasch, Linda A

AU - Boers, Maarten

AU - Hill, Catherine L

AU - Voshaar, Marieke

AU - Hoogland, Wijnanda

AU - de Wit, Maarten

AU - Flurey, Caroline

AU - Davis, Bev

AU - Hetland, Merete Lund

AU - Brahe, Cecilie Heegaard

AU - Gossec, Laure

AU - Wells, George A

AU - Tugwell, Peter

AU - Kuriya, Bindee

AU - Goel, Niti

AU - Singh, Jasvinder A

AU - Duarte, Cátia

AU - Da Silva, José

AU - van Schaardenburg, Dirkjan

AU - Proudman, Susanna

AU - van Tuyl, Lilian H D

AU - Working Group on the Patients’ Perspective on Remission in Rheumatoid Arthritis

PY - 2017/12/1

Y1 - 2017/12/1

N2 - OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.METHODS: A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.RESULTS: At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO.CONCLUSION: More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.

AB - OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored.METHODS: A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally.RESULTS: At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO.CONCLUSION: More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.

U2 - 10.3899/jrheum.161111

DO - 10.3899/jrheum.161111

M3 - Comment/debate

C2 - 28765250

SN - 0315-162X

VL - 44

SP - 1889

EP - 1893

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 12

ER -

Validating Rheumatoid Arthritis Remission Using the Patients' Perspective: Results from a Special Interest Group at OMERACT 2016

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