Abstract
The critical-size defect is important as an experimental model to test bone repair materials. Guided tissue regeneration is an established method for tissue regeneration within periodontal surgery. Bony defects covered by a membrane are allowed to be filled by bony tissue. Healing of 8-mm unicortical trephine defects was tested in Copenhagen White rabbit tibia using 3 different membranes. The critical-size defect in Copenhagen White rabbit tibia is larger than 8 mm, because control defects 8 mm in diameter healed spontaneously. However, it is anatomically not possible to create defects larger than 8 mm in an adult Copenhagen White rabbit tibia.
| Original language | English |
|---|---|
| Journal | Journal of Craniofacial Surgery |
| Volume | 5 |
| Issue number | 3 |
| Pages (from-to) | 201-3 |
| Number of pages | 3 |
| ISSN | 1049-2275 |
| Publication status | Published - 1 Jul 1994 |
Keywords
- Animals
- Bone Regeneration
- Disease Models, Animal
- Guided Tissue Regeneration
- Male
- Rabbits
- Tibia
- Wound Healing