Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat.

TY - JOUR

T1 - Ultrastructural immunocytochemical localization of chondroitin sulfate proteoglycan in Bruch's membrane of the rat.

AU - Lin, W L

AU - Essner, E

AU - McCarthy, K J

AU - Couchman, J R

N1 - Keywords: Animals; Antibodies, Monoclonal; Basement Membrane; Bruch Membrane; Capillaries; Chondroitin Sulfates; Choroid; Female; Immunoenzyme Techniques; Microscopy, Immunoelectron; Pigment Epithelium of Eye; Proteoglycans; Rats; Rats, Inbred Lew

PY - 1992

Y1 - 1992

N2 - Two monoclonal antibodies (Mab 4D5 and 2D6) raised against the core protein of a basement membrane chondroitin sulfate proteoglycan from Reichert's membrane of the rat, were used for ultrastructural immunoperoxidase localization of this protein in Bruch's membrane of the rat. Immunoreactivity for both antibodies was found in the basal lamina (basement membrane) of the choriocapillary endothelium and retinal pigment epithelium, in collagen fibers in the collagenous zones, and surrounding the elastic layer.

AB - Two monoclonal antibodies (Mab 4D5 and 2D6) raised against the core protein of a basement membrane chondroitin sulfate proteoglycan from Reichert's membrane of the rat, were used for ultrastructural immunoperoxidase localization of this protein in Bruch's membrane of the rat. Immunoreactivity for both antibodies was found in the basal lamina (basement membrane) of the choriocapillary endothelium and retinal pigment epithelium, in collagen fibers in the collagenous zones, and surrounding the elastic layer.

M3 - Journal article

C2 - 1582813

SN - 0146-0404

VL - 33

SP - 2072

EP - 2075

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

IS - 6

ER -