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Tumor-secreted LOXL2 activates fibroblasts through FAK signaling
Holly E Barker, Demelza Bird, Georgina Lang,
Janine T Erler
59
Citations (Scopus)
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Keyphrases
Fibroblasts
100%
Lysyl Oxidase
100%
Tumor
100%
Mammary Tumor Cells
16%
Tumor Metastasis
16%
Collagen Matrix
16%
Tumor Microenvironment
16%
Tumor Cell Invasion
16%
Host Tissues
8%
Orthotopic Model
8%
Activated Fibroblasts
8%
Antibody Inhibition
8%
Targeted Therapy
8%
Cancer-associated Fibroblasts
8%
Mammary Tumor
8%
Transgenic Mouse Model
8%
Recombinant
8%
Kinase Activation
8%
α-smooth muscle Actin (α-SMA)
8%
In Vitro Assay
8%
Cancer Progression
8%
Tumor Progression
8%
Parallel Alignment
8%
Novel Functions
8%
Host Cell
8%
Stromal Fibroblasts
8%
Fibroblast Activation
8%
Focal Adhesion Kinase
8%
Genetic Manipulation
8%
Extracellular Matrix
8%
Tumor Cells
8%
Cell-derived
8%
Integrin
8%
Medicine and Dentistry
Neoplasm
100%
Fibroblast
100%
Protein Lysine 6 Oxidase
100%
Metastatic Carcinoma
16%
Cell Invasion
16%
Breast Tumor
16%
Tumor Microenvironment
16%
Tumor Cell
16%
Host Cell
8%
Integrin
8%
Tumor Progression
8%
Focal Adhesion Kinase
8%
Extracellular Matrix
8%
Smooth Muscle Actin
8%
Targeted Therapy
8%
Cancer Growth
8%
In Vitro
8%
Janus Kinase 1
8%
Biochemistry, Genetics and Molecular Biology
Lysyl Oxidase
100%
Fibroblast
100%
Cell Invasion
16%
Genetic Manipulation
8%
Tumor Progression
8%
Actin
8%
Janus Kinase 1
8%
Integrin
8%
Transgenics
8%
Mouse Model
8%