Trihydroxytrioxatriangulene - An Extended Fluorescein and a Ratiometric pH Sensor

Fredrik Westerlund; Christoffer Boli Hildebrandt; Thomas Just Sørensen; Bo Wegge Laursen

doi:10.1002/chem.200902965

Trihydroxytrioxatriangulene - An Extended Fluorescein and a Ratiometric pH Sensor

Fredrik Westerlund, Christoffer Boli Hildebrandt, Thomas Just Sørensen, Bo Wegge Laursen

Department of Chemistry

38 Citations (Scopus)

Abstract

(Figure Presented) Fluorescein ver. 2.0: A new, highly fluorescent, pH-sensitive trihydroxytrioxatriangulenium dye (H-TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two-dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.

Original language	English
Journal	Chemistry: A European Journal
Volume	16
Issue number	10
Pages (from-to)	2992 - 2996
Number of pages	4
ISSN	0947-6539
DOIs	https://doi.org/10.1002/chem.200902965
Publication status	Published - 8 Mar 2010

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abstract = "(Figure Presented) Fluorescein ver. 2.0: A new, highly fluorescent, pH-sensitive trihydroxytrioxatriangulenium dye (H-TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two-dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.",

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AU - Westerlund, Fredrik

AU - Hildebrandt, Christoffer Boli

AU - Sørensen, Thomas Just

AU - Laursen, Bo Wegge

PY - 2010/3/8

Y1 - 2010/3/8

N2 - (Figure Presented) Fluorescein ver. 2.0: A new, highly fluorescent, pH-sensitive trihydroxytrioxatriangulenium dye (H-TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two-dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.

AB - (Figure Presented) Fluorescein ver. 2.0: A new, highly fluorescent, pH-sensitive trihydroxytrioxatriangulenium dye (H-TOTA) has been synthesised and characterised. The dye is closely related to fluorescein and may be considered to be a two-dimensional extended version. This new dye can exist in four different protonation states (see graphic) depending on the pH, and its use as a sensitive fluorescent ratiometric pH probe in a physiological buffer is demonstrated.

U2 - 10.1002/chem.200902965

DO - 10.1002/chem.200902965

M3 - Journal article

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SN - 0947-6539

VL - 16

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EP - 2996

JO - Chemistry: A European Journal

JF - Chemistry: A European Journal

IS - 10

ER -

Trihydroxytrioxatriangulene - An Extended Fluorescein and a Ratiometric pH Sensor

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