Triage for selection to colonoscopy?

For the Danish Collaborative Group on Early Detection of Colorectal Neoplasia

doi:10.1016/j.ejso.2018.06.013

Triage for selection to colonoscopy?

For the Danish Collaborative Group on Early Detection of Colorectal Neoplasia

4 Citations (Scopus)

Abstract

Implementation of population screening for colorectal cancer by direct colonoscopy or follow-up colonoscopy after a positive fecal blood test has challenged the overall capacity of bowel examinations. Certain countries are facing serious colonoscopy capacity constraints, which have led to waiting lists and long-time latency of follow-up examinations. Various options for improvement are considered, including increased cut-off values of the fecal blood tests. Results from major clinical studies of blood-based, cancer-associated biomarkers have led to focus, however, on a triage concept for improved selection to colonoscopy. The triage test may include subject age, concentration of hemoglobin in a feces test and a combination of certain blood-based cancer associated biomarkers. Recent results have indicated that triage may reduce the requirements for colonoscopy by around 30%. Such results may be advantageous for the capacity, the heath budgets and in particular, the subjects, who do not need an unnecessary, unpleasant and risk-associated bowel examination.

Original language	English
Journal	European Journal of Surgical Oncology
Volume	44
Issue number	10
Pages (from-to)	1539-1541
Number of pages	3
ISSN	0748-7983
DOIs	https://doi.org/10.1016/j.ejso.2018.06.013
Publication status	Published - 2018

Keywords

Biomarkers
Blood test
Colonoscopy
Colorectal cancer
Screening
Triage

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ejso.2018.06.013

Cite this

@article{bf0fc6f9ad454e60aeef6d786e836384,

title = "Triage for selection to colonoscopy?",

abstract = "Implementation of population screening for colorectal cancer by direct colonoscopy or follow-up colonoscopy after a positive fecal blood test has challenged the overall capacity of bowel examinations. Certain countries are facing serious colonoscopy capacity constraints, which have led to waiting lists and long-time latency of follow-up examinations. Various options for improvement are considered, including increased cut-off values of the fecal blood tests. Results from major clinical studies of blood-based, cancer-associated biomarkers have led to focus, however, on a triage concept for improved selection to colonoscopy. The triage test may include subject age, concentration of hemoglobin in a feces test and a combination of certain blood-based cancer associated biomarkers. Recent results have indicated that triage may reduce the requirements for colonoscopy by around 30%. Such results may be advantageous for the capacity, the heath budgets and in particular, the subjects, who do not need an unnecessary, unpleasant and risk-associated bowel examination.",

keywords = "Biomarkers, Blood test, Colonoscopy, Colorectal cancer, Screening, Triage",

author = "Mathias Mertz-Petersen and Piper, {Thomas B.} and Jakob Kleif and Linnea Ferm and Christensen, {Ib Jarle} and Nielsen, {Hans J.} and J{\o}rgensen, {Lars Nannestad} and Morten Rasmussen and Jakob Hendel and Madsen, {Mogens R.} and Madsen, {Anders Husted} and Jesper Vilandt and Thore Hillig and Karina Willemoes and S{\o}ren Brandsborg and Michael Kl{\ae}rke and Andersen, {Berit S.} and Nete Hornung and K{\aa}re Sunesen and Andersen, {Claus L.} and Erland Erlandsen and Ali Kahlid and {For the Danish Collaborative Group on Early Detection of Colorectal Neoplasia}",

year = "2018",

doi = "10.1016/j.ejso.2018.06.013",

language = "English",

volume = "44",

pages = "1539--1541",

journal = "European Journal of Surgical Oncology",

issn = "0748-7983",