The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment

Nanette M M M Debes; Helle Hjalgrim; Liselotte Skov; Nanette M M M Debes; Helle Hjalgrim; Liselotte Skov

doi:10.1177/0883073808331363

The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment

Nanette M M M Debes, Helle Hjalgrim, Liselotte Skov, Nanette M M M Debes, Helle Hjalgrim, Liselotte Skov

15 Citations (Scopus)

Abstract

Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.

Original language	English
Journal	Journal of Child Neurology
Volume	24
Issue number	12
Pages (from-to)	1504-12
Number of pages	8
ISSN	0883-0738
DOIs	https://doi.org/10.1177/0883073808331363 https://doi.org/10.1177/0883073808331363
Publication status	Published - 2009

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@article{9953ebc0a60711df928f000ea68e967b,

title = "The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment",

abstract = "Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.",

author = "Debes, {Nanette M M M} and Helle Hjalgrim and Liselotte Skov and Debes, {Nanette M M M} and Helle Hjalgrim and Liselotte Skov",

note = "Keywords: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Therapy; Cohort Studies; Comorbidity; Denmark; Dietary Supplements; Female; Humans; Interviews as Topic; Male; Neuropharmacology; Obsessive-Compulsive Disorder; Scandinavia; Serotonin Uptake Inhibitors; Tourette Syndrome; Treatment Outcome; Young Adult",

year = "2009",

doi = "10.1177/0883073808331363",

language = "English",

volume = "24",

pages = "1504--12",

journal = "Journal of Child Neurology",

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publisher = "SAGE Publications",

number = "12",

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TY - JOUR

T1 - The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment

AU - Debes, Nanette M M M

AU - Hjalgrim, Helle

AU - Skov, Liselotte

AU - Debes, Nanette M M M

AU - Hjalgrim, Helle

AU - Skov, Liselotte

N1 - Keywords: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Therapy; Cohort Studies; Comorbidity; Denmark; Dietary Supplements; Female; Humans; Interviews as Topic; Male; Neuropharmacology; Obsessive-Compulsive Disorder; Scandinavia; Serotonin Uptake Inhibitors; Tourette Syndrome; Treatment Outcome; Young Adult

PY - 2009

Y1 - 2009

N2 - Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.

AB - Tourette syndrome is often accompanied by other syndromes, like attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder, and its treatment is symptomatic. Because there are no European guidelines for pharmacological treatment in Tourette syndrome, we wanted to contribute to a better insight into the common practice in Scandinavia. Furthermore, we wanted to elaborate the influence of the presence of comorbidities and of the severity of tics on pharmacological treatment. We have examined the frequency, art, and reason for pharmacological treatment in a Danish clinical cohort of 314 children with Tourette syndrome. In total, 60.5% of the children once had received pharmacological treatment. Mostly, the treatment was started because of tics or ADHD. If ADHD or obsessive-compulsive disorder were present, more children received pharmacological treatment and more different agents were tried. The children who received pharmacological treatment had more severe tics than those without medication.

U2 - 10.1177/0883073808331363

DO - 10.1177/0883073808331363

M3 - Journal article

C2 - 19494355

SN - 0883-0738

VL - 24

SP - 1504

EP - 1512

JO - Journal of Child Neurology

JF - Journal of Child Neurology

IS - 12

ER -

The presence of comorbidity in Tourette syndrome increases the need for pharmacological treatment

Abstract

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