The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

Ana Portero; Carmen Remuñán-López; Hanne Mørck Nielsen

The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

Ana Portero, Carmen Remuñán-López, Hanne Mørck Nielsen

67 Citations (Scopus)

Abstract

To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.

Original language	English
Journal	Pharmaceutical Research
Volume	19
Issue number	2
Pages (from-to)	169-74
Number of pages	6
ISSN	0724-8741
Publication status	Published - 2002

Keywords

Absorption
Cells, Cultured
Chemistry, Physical
Chitin
Chitosan
Excipients
Fluorescein-5-isothiocyanate
Fluorescent Dyes
Glutamic Acid
Humans
Mannitol
Molecular Weight
Mouth Mucosa
Peptides
Permeability
Physicochemical Phenomena
Proteins
Stimulation, Chemical

Cite this

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title = "The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium",

abstract = "To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.",

keywords = "Absorption, Cells, Cultured, Chemistry, Physical, Chitin, Chitosan, Excipients, Fluorescein-5-isothiocyanate, Fluorescent Dyes, Glutamic Acid, Humans, Mannitol, Molecular Weight, Mouth Mucosa, Peptides, Permeability, Physicochemical Phenomena, Proteins, Stimulation, Chemical",

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pages = "169--74",

journal = "Pharmaceutical Research",

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T1 - The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

AU - Portero, Ana

AU - Remuñán-López, Carmen

AU - Nielsen, Hanne Mørck

PY - 2002

Y1 - 2002

N2 - To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.

AB - To investigate the potential of chitosan (CS) to enhance buccal peptide and protein absorption, the TR146 cell culture model, a model of the buccal epithelium, was used.

KW - Absorption

KW - Cells, Cultured

KW - Chemistry, Physical

KW - Chitin

KW - Chitosan

KW - Excipients

KW - Fluorescein-5-isothiocyanate

KW - Fluorescent Dyes

KW - Glutamic Acid

KW - Humans

KW - Mannitol

KW - Molecular Weight

KW - Mouth Mucosa

KW - Peptides

KW - Permeability

KW - Physicochemical Phenomena

KW - Proteins

KW - Stimulation, Chemical

M3 - Journal article

C2 - 11883644

SN - 0724-8741

VL - 19

SP - 169

EP - 174

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 2

ER -

The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium

Abstract

Keywords

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