The great debate: varicocele treatment and impact on fertility

Matthew A Will; Jason Swain; Mikkel Fode; Jens Sonksen; Gregory M Christman; Dana Ohl

doi:10.1016/j.fertnstert.2011.01.002

The great debate: varicocele treatment and impact on fertility

Matthew A Will, Jason Swain, Mikkel Fode, Jens Sonksen, Gregory M Christman, Dana Ohl

90 Citations (Scopus)

Abstract

Objective: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. Design: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. Conclusion(s): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).

Original language	English
Journal	Fertility and Sterility
Volume	95
Issue number	3
Pages (from-to)	841-52
Number of pages	12
ISSN	0015-0282
DOIs	https://doi.org/10.1016/j.fertnstert.2011.01.002
Publication status	Published - 1 Mar 2011

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title = "The great debate: varicocele treatment and impact on fertility",

abstract = "Objective: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. Design: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. Conclusion(s): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).",

author = "Will, {Matthew A} and Jason Swain and Mikkel Fode and Jens Sonksen and Christman, {Gregory M} and Dana Ohl",

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T1 - The great debate: varicocele treatment and impact on fertility

AU - Will, Matthew A

AU - Swain, Jason

AU - Fode, Mikkel

AU - Sonksen, Jens

AU - Christman, Gregory M

AU - Ohl, Dana

PY - 2011/3/1

Y1 - 2011/3/1

N2 - Objective: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. Design: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. Conclusion(s): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).

AB - Objective: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. Design: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. Conclusion(s): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).

U2 - 10.1016/j.fertnstert.2011.01.002

DO - 10.1016/j.fertnstert.2011.01.002

M3 - Review

SN - 0015-0282

VL - 95

SP - 841

EP - 852

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 3

ER -

The great debate: varicocele treatment and impact on fertility

Abstract

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