The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects

K Yanagisawa; Lesli Hingstrup Larsen; G Andersen; T Drivsholm; A Cederberg; R Westergren; K Borch-Johnsen; O Pedersen; S Enerbäck; T Hansen

doi:10.1007/s00125-003-1213-6

The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects

K Yanagisawa, Lesli Hingstrup Larsen, G Andersen, T Drivsholm, A Cederberg, R Westergren, K Borch-Johnsen, O Pedersen, S Enerbäck, T Hansen

17 Citations (Scopus)

Abstract

The transcription factor FOXC2 plays a key role in adipocyte differentiation and the FOXC2 gene is a candidate gene for Type 2 diabetes, obesity and dyslipidaemia. We investigated whether the FOXC2 -512C>T promoter variant is associated with Type 2 diabetes or its intermediary phenotypes in glucose tolerant subjects.

Original language	English
Journal	Diabetologia
Volume	46
Issue number	11
Pages (from-to)	1576-1580
Number of pages	5
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-003-1213-6
Publication status	Published - 1 Nov 2003

Keywords

Base Sequence
Body Constitution
C-Peptide
DNA Primers
DNA-Binding Proteins
Denmark
Diabetes Mellitus
European Continental Ancestry Group
Female
Forkhead Transcription Factors
Genetic Variation
Glucose Tolerance Test
Humans
Male
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Reference Values
Sequence Deletion
Transcription Factors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00125-003-1213-6

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Yanagisawa, K., Larsen, L. H., Andersen, G., Drivsholm, T., Cederberg, A., Westergren, R., Borch-Johnsen, K., Pedersen, O., Enerbäck, S., & Hansen, T. (2003). The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects. Diabetologia, 46(11), 1576-1580. https://doi.org/10.1007/s00125-003-1213-6

Yanagisawa, K, Larsen, LH, Andersen, G, Drivsholm, T, Cederberg, A, Westergren, R, Borch-Johnsen, K, Pedersen, O, Enerbäck, S & Hansen, T 2003, 'The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects', Diabetologia, vol. 46, no. 11, pp. 1576-1580. https://doi.org/10.1007/s00125-003-1213-6

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abstract = "The transcription factor FOXC2 plays a key role in adipocyte differentiation and the FOXC2 gene is a candidate gene for Type 2 diabetes, obesity and dyslipidaemia. We investigated whether the FOXC2 -512C>T promoter variant is associated with Type 2 diabetes or its intermediary phenotypes in glucose tolerant subjects.",

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AU - Yanagisawa, K

AU - Larsen, Lesli Hingstrup

AU - Andersen, G

AU - Drivsholm, T

AU - Cederberg, A

AU - Westergren, R

AU - Borch-Johnsen, K

AU - Pedersen, O

AU - Enerbäck, S

AU - Hansen, T

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AB - The transcription factor FOXC2 plays a key role in adipocyte differentiation and the FOXC2 gene is a candidate gene for Type 2 diabetes, obesity and dyslipidaemia. We investigated whether the FOXC2 -512C>T promoter variant is associated with Type 2 diabetes or its intermediary phenotypes in glucose tolerant subjects.

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KW - Body Constitution

KW - C-Peptide

KW - DNA Primers

KW - DNA-Binding Proteins

KW - Denmark

KW - Diabetes Mellitus

KW - European Continental Ancestry Group

KW - Female

KW - Forkhead Transcription Factors

KW - Genetic Variation

KW - Glucose Tolerance Test

KW - Humans

KW - Male

KW - Polymerase Chain Reaction

KW - Polymorphism, Restriction Fragment Length

KW - Reference Values

KW - Sequence Deletion

KW - Transcription Factors

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DO - 10.1007/s00125-003-1213-6

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C2 - 14530861

SN - 0012-186X

VL - 46

SP - 1576

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JO - Diabetologia

JF - Diabetologia

IS - 11

ER -

The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects

Abstract

Keywords

UN SDGs

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