The effect of metrizamide on regional brain glucose metabolism in the rat.

L Bech, N H Diemer, A Gjedde

12 Citations (Scopus)

Abstract

The X-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation in vitro. In vivo, the present autoradiographic study with labeled 2-deoxyglucose revealed a global reduction of brain glucose phosphorylation after metrizamide administration in the cisterna magna of rats. The reduction averaged 18% of all regions.
Original languageEnglish
JournalActa Neurologica Scandinavica
Volume69
Issue number4
Pages (from-to)249-53
Number of pages4
ISSN0001-6314
Publication statusPublished - 1984
Externally publishedYes

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