The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

M. Mann, N.A. Kulak, N. Nagaraj, J. Cox

262 Citations (Scopus)

Abstract

High-resolution mass spectrometry (MS)-based proteomics has progressed tremendously over the years. For model organisms like yeast, we can now quantify complete proteomes in just a few hours. Developments discussed in this Perspective will soon enable complete proteome analysis of mammalian cells, as well, with profound impact on biology and biomedicine.
Original languageEnglish
JournalMolecular Cell
Volume49
Issue number4
Pages (from-to)583-590
Number of pages8
ISSN1097-2765
DOIs
Publication statusPublished - 21 Feb 2013

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