The Center for Integrated Molecular Brain Imaging (Cimbi) database

Gitte M Knudsen; Peter S Jensen; David Erritzoe; William F C Baaré; Anders Ettrup; Patrick M Fisher; Nic Gillings; Hanne D Hansen; Lars Kai Hansen; Steen G Hasselbalch; Susanne Henningsson; Matthias Manfred Herth; Klaus K Holst; Pernille Iversen; Lars V Kessing; Julian Macoveanu; Kathrine Skak Madsen; Erik L Mortensen; Finn Årup Nielsen; Olaf B Paulson; Hartwig R Siebner; Dea S Stenbæk; Claus Svarer; Terry L Jernigan; Stephen C Strother; Vibe G Frokjaer

doi:10.1016/j.neuroimage.2015.04.025

The Center for Integrated Molecular Brain Imaging (Cimbi) database

Gitte M Knudsen, Peter S Jensen, David Erritzoe, William F C Baaré, Anders Ettrup, Patrick M Fisher, Nic Gillings, Hanne D Hansen, Lars Kai Hansen, Steen G Hasselbalch, Susanne Henningsson, Matthias Manfred Herth, Klaus K Holst, Pernille Iversen, Lars V Kessing, Julian Macoveanu, Kathrine Skak Madsen, Erik L Mortensen, Finn Årup Nielsen, Olaf B PaulsonHartwig R Siebner, Dea S Stenbæk, Claus Svarer, Terry L Jernigan, Stephen C Strother, Vibe G Frokjaer

35 Citations (Scopus)

Abstract

We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes. The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests. The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.

Original language	English
Journal	NeuroImage
Volume	124
Issue number	Part B
Pages (from-to)	1213-19
Number of pages	8
ISSN	1053-8119
DOIs	https://doi.org/10.1016/j.neuroimage.2015.04.025
Publication status	Published - 1 Jan 2016

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Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., ... Frokjaer, V. G. (2016). The Center for Integrated Molecular Brain Imaging (Cimbi) database. NeuroImage, 124 (Part B), 1213-19. https://doi.org/10.1016/j.neuroimage.2015.04.025

Knudsen, GM, Jensen, PS, Erritzoe, D, Baaré, WFC, Ettrup, A, Fisher, PM, Gillings, N, Hansen, HD, Hansen, LK, Hasselbalch, SG, Henningsson, S, Herth, MM, Holst, KK, Iversen, P, Kessing, LV, Macoveanu, J, Madsen, KS, Mortensen, EL, Nielsen, FÅ, Paulson, OB , Siebner, HR, Stenbæk, DS, Svarer, C, Jernigan, TL, Strother, SC & Frokjaer, VG 2016, 'The Center for Integrated Molecular Brain Imaging (Cimbi) database', NeuroImage, vol. 124 , no. Part B, pp. 1213-19. https://doi.org/10.1016/j.neuroimage.2015.04.025

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title = "The Center for Integrated Molecular Brain Imaging (Cimbi) database",

abstract = "We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes. The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests. The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.",

author = "Knudsen, {Gitte M} and Jensen, {Peter S} and David Erritzoe and Baar{\'e}, {William F C} and Anders Ettrup and Fisher, {Patrick M} and Nic Gillings and Hansen, {Hanne D} and Hansen, {Lars Kai} and Hasselbalch, {Steen G} and Susanne Henningsson and Herth, {Matthias Manfred} and Holst, {Klaus K} and Pernille Iversen and Kessing, {Lars V} and Julian Macoveanu and Madsen, {Kathrine Skak} and Mortensen, {Erik L} and Nielsen, {Finn {\AA}rup} and Paulson, {Olaf B} and Siebner, {Hartwig R} and Stenb{\ae}k, {Dea S} and Claus Svarer and Jernigan, {Terry L} and Strother, {Stephen C} and Frokjaer, {Vibe G}",

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AU - Knudsen, Gitte M

AU - Jensen, Peter S

AU - Erritzoe, David

AU - Baaré, William F C

AU - Ettrup, Anders

AU - Fisher, Patrick M

AU - Gillings, Nic

AU - Hansen, Hanne D

AU - Hansen, Lars Kai

AU - Hasselbalch, Steen G

AU - Henningsson, Susanne

AU - Herth, Matthias Manfred

AU - Holst, Klaus K

AU - Iversen, Pernille

AU - Kessing, Lars V

AU - Macoveanu, Julian

AU - Madsen, Kathrine Skak

AU - Mortensen, Erik L

AU - Nielsen, Finn Årup

AU - Paulson, Olaf B

AU - Siebner, Hartwig R

AU - Stenbæk, Dea S

AU - Svarer, Claus

AU - Jernigan, Terry L

AU - Strother, Stephen C

AU - Frokjaer, Vibe G

PY - 2016/1/1

Y1 - 2016/1/1

N2 - We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes. The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests. The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.

AB - We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT4 and the 5-HT transporter (5-HTT), but can easily serve other purposes. The Cimbi database and Cimbi biobank were formally established in 2008 with the purpose to store the wealth of Cimbi-acquired data in a highly structured and standardized manner in accordance with the regulations issued by the Danish Data Protection Agency as well as to provide a quality-controlled resource for future hypothesis-generating and hypothesis-driven studies. The Cimbi database currently comprises a total of 1100 PET and 1000 structural and functional MRI scans and it holds a multitude of additional data, such as genetic and biochemical data, and scores from 17 self-reported questionnaires and from 11 neuropsychological paper/computer tests. The database associated Cimbi biobank currently contains blood and in some instances saliva samples from about 500 healthy volunteers and 300 patients with e.g., major depression, dementia, substance abuse, obesity, and impulsive aggression. Data continue to be added to the Cimbi database and biobank.

U2 - 10.1016/j.neuroimage.2015.04.025

DO - 10.1016/j.neuroimage.2015.04.025

M3 - Journal article

C2 - 25891375

SN - 1053-8119

VL - 124

SP - 1213

EP - 1219

JO - NeuroImage

JF - NeuroImage

IS - Part B

ER -

The Center for Integrated Molecular Brain Imaging (Cimbi) database

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