T-cell responses in malaria

L Hviid, P H Jakobsen, Y A Abu-Zeid, T G Theander

8 Citations (Scopus)

Abstract

Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.
Original languageEnglish
JournalActa Pathologica Microbiologica et Immunologica Scandinavica
Volume100
Issue number2
Pages (from-to)95-106
Number of pages11
ISSN0903-4641
Publication statusPublished - 1992

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