Roed, H., Frederiksen, J., Langkilde, A. R., Sørensen, T. L., Lauritzen, M., & Sellebjerg, F. (2005). Systemic T-cell activation in acute clinically isolated optic neuritis. Journal of Neuroimmunology, 162(1-2), 165-172. http://www.ncbi.nlm.nih.gov//entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15833372
Systemic T-cell activation in acute clinically isolated optic neuritis. / Roed, Hanne; Frederiksen, Jette
; Langkilde, Annika Reynberg et al.
In:
Journal of Neuroimmunology, Vol. 162, No. 1-2, 2005, p. 165-172.
Research output: Contribution to journal › Journal article › Research › peer-review
Roed, H, Frederiksen, J, Langkilde, AR, Sørensen, TL, Lauritzen, M & Sellebjerg, F 2005, 'Systemic T-cell activation in acute clinically isolated optic neuritis.', Journal of Neuroimmunology, vol. 162, no. 1-2, pp. 165-172. <http://www.ncbi.nlm.nih.gov//entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15833372>
Roed H, Frederiksen J, Langkilde AR, Sørensen TL, Lauritzen M, Sellebjerg F. Systemic T-cell activation in acute clinically isolated optic neuritis. Journal of Neuroimmunology. 2005;162(1-2):165-172.
Roed, Hanne ; Frederiksen, Jette ; Langkilde, Annika Reynberg et al. / Systemic T-cell activation in acute clinically isolated optic neuritis. In: Journal of Neuroimmunology. 2005 ; Vol. 162, No. 1-2. pp. 165-172.
@article{ed4145515cac457fb7f827ae1e3d7322,
title = "Systemic T-cell activation in acute clinically isolated optic neuritis.",
abstract = "We examined untreated 60 patients with acute monosymptomatic optic neuritis (ON). Patients examined early after onset showed increased expression of HLA-DR and CD45R0 on CD4 and CD8 T cells. Expression of HLA-DR on CD4 T cells was higher in patients without IgG oligoclonal bands. Expression of HLA-DR on CD4 and CD8 T cells correlated negatively with measures of disease activity and positively with measures of good visual function, and expression of CD45R0 on CD4 T cells correlated negatively with measures of disease activity. We hypothesize that HLA-DR expression may characterize a protective T-cell subset in ON",
author = "Hanne Roed and Jette Frederiksen and Langkilde, {Annika Reynberg} and S{\o}rensen, {Torben Lykke} and Martin Lauritzen and Finn Sellebjerg",
year = "2005",
language = "English",
volume = "162",
pages = "165--172",
journal = "Journal of Neuroimmunology",
issn = "0165-5728",
publisher = "Elsevier",
number = "1-2",
}
TY - JOUR
T1 - Systemic T-cell activation in acute clinically isolated optic neuritis.
AU - Roed, Hanne
AU - Frederiksen, Jette
AU - Langkilde, Annika Reynberg
AU - Sørensen, Torben Lykke
AU - Lauritzen, Martin
AU - Sellebjerg, Finn
PY - 2005
Y1 - 2005
N2 - We examined untreated 60 patients with acute monosymptomatic optic neuritis (ON). Patients examined early after onset showed increased expression of HLA-DR and CD45R0 on CD4 and CD8 T cells. Expression of HLA-DR on CD4 T cells was higher in patients without IgG oligoclonal bands. Expression of HLA-DR on CD4 and CD8 T cells correlated negatively with measures of disease activity and positively with measures of good visual function, and expression of CD45R0 on CD4 T cells correlated negatively with measures of disease activity. We hypothesize that HLA-DR expression may characterize a protective T-cell subset in ON
AB - We examined untreated 60 patients with acute monosymptomatic optic neuritis (ON). Patients examined early after onset showed increased expression of HLA-DR and CD45R0 on CD4 and CD8 T cells. Expression of HLA-DR on CD4 T cells was higher in patients without IgG oligoclonal bands. Expression of HLA-DR on CD4 and CD8 T cells correlated negatively with measures of disease activity and positively with measures of good visual function, and expression of CD45R0 on CD4 T cells correlated negatively with measures of disease activity. We hypothesize that HLA-DR expression may characterize a protective T-cell subset in ON
M3 - Journal article
SN - 0165-5728
VL - 162
SP - 165
EP - 172
JO - Journal of Neuroimmunology
JF - Journal of Neuroimmunology
IS - 1-2
ER -