Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

Stefanie Kickinger; Anas Al-Khawaja; Anne Staehr Haugaard; Rebekka Loeffler; Maria Damgaard; Gerhard Eckert; Bente Frolund; Petrine Wellendorph

Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

Stefanie Kickinger, Anas Al-Khawaja, Anne Staehr Haugaard, Rebekka Loeffler, Maria Damgaard, Gerhard Eckert, Bente Frolund, Petrine Wellendorph

Department of Drug Design and Pharmacology

Original language	English
Publication date	19 Aug 2018
Publication status	Published - 19 Aug 2018
Event	256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond - Boston, MA, United States Duration: 19 Aug 2018 → 23 Aug 2018 Conference number: 189

Conference

Conference	256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond
Number	189
Location	Boston, MA
Country/Territory	United States
Period	19/08/2018 → 23/08/2018

Cite this

Kickinger, S., Al-Khawaja, A., Haugaard, A. S., Loeffler, R., Damgaard, M., Eckert, G., Frolund, B., & Wellendorph, P. (2018). Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. / Kickinger, Stefanie; Al-Khawaja, Anas; Haugaard, Anne Staehr et al.

2018. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Kickinger, S, Al-Khawaja, A, Haugaard, AS, Loeffler, R, Damgaard, M, Eckert, G, Frolund, B & Wellendorph, P 2018, 'Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors', 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States, 19/08/2018 - 23/08/2018.

Kickinger S, Al-Khawaja A, Haugaard AS, Loeffler R, Damgaard M, Eckert G et al.. Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. 2018. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

Kickinger, Stefanie ; Al-Khawaja, Anas ; Haugaard, Anne Staehr et al. / Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

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title = "Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors",

author = "Stefanie Kickinger and Anas Al-Khawaja and Haugaard, {Anne Staehr} and Rebekka Loeffler and Maria Damgaard and Gerhard Eckert and Bente Frolund and Petrine Wellendorph",

year = "2018",

month = aug,

day = "19",

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note = "256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond ; Conference date: 19-08-2018 Through 23-08-2018",

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TY - ABST

T1 - Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

AU - Kickinger, Stefanie

AU - Al-Khawaja, Anas

AU - Haugaard, Anne Staehr

AU - Loeffler, Rebekka

AU - Damgaard, Maria

AU - Eckert, Gerhard

AU - Frolund, Bente

AU - Wellendorph, Petrine

N1 - Conference code: 189

PY - 2018/8/19

Y1 - 2018/8/19

UR - https://global.acs.org/events/256th-acs-national-meeting-exposition/

M3 - Conference abstract for conference

T2 - 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond

Y2 - 19 August 2018 through 23 August 2018

ER -

Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

Conference

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