Abstract
Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.
| Original language | English |
|---|---|
| Journal | Current Opinion in Cell Biology |
| Volume | 13 |
| Issue number | 5 |
| Pages (from-to) | 578-83 |
| Number of pages | 5 |
| ISSN | 0955-0674 |
| Publication status | Published - 2001 |