Surgical treatment and follow up on undescended testis

Jørgen Mogens Thorup; D. Cortes

Surgical treatment and follow up on undescended testis

10 Citations (Scopus)

Abstract

With skill and ability to control a variety of operative techniques, undescended testes can be placed in the scrotum with 90% success rate in palpable testes and 85% in abdominal testes. Long term results are related also to the variability of the disease. A hypothesis that in cryptorchid testes a common etiologic antenatal factor is associated with infertility and/or testicular malignancy is supported by the finding of the influence of maternal lifestyle factors on fertility, a relative cancer risk of OR: 2.0 in contralateral descended testis of unilateral cryptorchidism, impaired germ cell number at birth in some cryptorchid testes and Intratubular Germ Cell Neoplasia seen in early childhood. The hypothesis that the abnormal location of the testis exposes the testis to infertility and malignant transformation is supported by the findings of early treatment lowering the risk of both infertility and testicular cancer. Disrupted endocrine regulation may be combined with both hypotheses
Udgivelsesdato: 2009/9

Original language	English
Journal	Pediatric Endocrinology Reviews
Volume	7
Issue number	1
Pages (from-to)	38-43
Number of pages	5
ISSN	1565-4753
Publication status	Published - 2009

Cite this

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title = "Surgical treatment and follow up on undescended testis",

abstract = "With skill and ability to control a variety of operative techniques, undescended testes can be placed in the scrotum with 90% success rate in palpable testes and 85% in abdominal testes. Long term results are related also to the variability of the disease. A hypothesis that in cryptorchid testes a common etiologic antenatal factor is associated with infertility and/or testicular malignancy is supported by the finding of the influence of maternal lifestyle factors on fertility, a relative cancer risk of OR: 2.0 in contralateral descended testis of unilateral cryptorchidism, impaired germ cell number at birth in some cryptorchid testes and Intratubular Germ Cell Neoplasia seen in early childhood. The hypothesis that the abnormal location of the testis exposes the testis to infertility and malignant transformation is supported by the findings of early treatment lowering the risk of both infertility and testicular cancer. Disrupted endocrine regulation may be combined with both hypotheses Udgivelsesdato: 2009/9",

author = "Thorup, {J{\o}rgen Mogens} and D. Cortes",

note = "Keywords: Age Factors; Causality; Cryptorchidism; Endocrine Surgical Procedures; Follow-Up Studies; Humans; Infertility; Male; Risk Factors; Testicular Neoplasms; Testis; Treatment Outcome",

year = "2009",

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journal = "Pediatric Endocrinology Reviews",

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T1 - Surgical treatment and follow up on undescended testis

AU - Thorup, Jørgen Mogens

AU - Cortes, D.

N1 - Keywords: Age Factors; Causality; Cryptorchidism; Endocrine Surgical Procedures; Follow-Up Studies; Humans; Infertility; Male; Risk Factors; Testicular Neoplasms; Testis; Treatment Outcome

PY - 2009

Y1 - 2009

N2 - With skill and ability to control a variety of operative techniques, undescended testes can be placed in the scrotum with 90% success rate in palpable testes and 85% in abdominal testes. Long term results are related also to the variability of the disease. A hypothesis that in cryptorchid testes a common etiologic antenatal factor is associated with infertility and/or testicular malignancy is supported by the finding of the influence of maternal lifestyle factors on fertility, a relative cancer risk of OR: 2.0 in contralateral descended testis of unilateral cryptorchidism, impaired germ cell number at birth in some cryptorchid testes and Intratubular Germ Cell Neoplasia seen in early childhood. The hypothesis that the abnormal location of the testis exposes the testis to infertility and malignant transformation is supported by the findings of early treatment lowering the risk of both infertility and testicular cancer. Disrupted endocrine regulation may be combined with both hypotheses Udgivelsesdato: 2009/9

AB - With skill and ability to control a variety of operative techniques, undescended testes can be placed in the scrotum with 90% success rate in palpable testes and 85% in abdominal testes. Long term results are related also to the variability of the disease. A hypothesis that in cryptorchid testes a common etiologic antenatal factor is associated with infertility and/or testicular malignancy is supported by the finding of the influence of maternal lifestyle factors on fertility, a relative cancer risk of OR: 2.0 in contralateral descended testis of unilateral cryptorchidism, impaired germ cell number at birth in some cryptorchid testes and Intratubular Germ Cell Neoplasia seen in early childhood. The hypothesis that the abnormal location of the testis exposes the testis to infertility and malignant transformation is supported by the findings of early treatment lowering the risk of both infertility and testicular cancer. Disrupted endocrine regulation may be combined with both hypotheses Udgivelsesdato: 2009/9

M3 - Journal article

C2 - 19696715

SN - 1565-4753

VL - 7

SP - 38

EP - 43

JO - Pediatric Endocrinology Reviews

JF - Pediatric Endocrinology Reviews

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