TY - JOUR
T1 - Subjective quality of life in first-episode psychosis
T2 - A ten year follow-up study
AU - Gardsjord, Erlend Strand
AU - Romm, Kristin Lie
AU - Friis, Svein
AU - Barder, Helene Eidsmo
AU - Evensen, Julie
AU - Haahr, Ulrik
AU - Ten Velden Hegelstad, Wenche
AU - Joa, Inge
AU - Johannessen, Jan Olav
AU - Langeveld, Johannes
AU - Larsen, Tor Ketil
AU - Opjordsmoen, Stein
AU - Rund, Bjørn Rishovd
AU - Simonsen, Erik
AU - Vaglum, Per
AU - McGlashan, Thomas
AU - Melle, Ingrid
AU - Røssberg, Jan Ivar
N1 - Copyright © 2016 Elsevier B.V. All rights reserved.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Subjective quality of life (S-QoL) is an important outcome measure in first episode psychosis (FEP). The aims of this study were to describe S-QoL-development the first 10-years in FEP patients and to identify predictors of this development. Methods: A representative sample of 272 patients with a first episode psychotic disorder was included from 1997 through 2000. At 10 year follow-up 186 patients participated. QoL was measured by the Lehman's Quality of Life Interview. Linear mixed model analyses were performed to investigate longitudinal effects of baseline psychiatric symptoms and socio-economic variables and the effects of changes in the same variables on S-QoL-development. Results: S-QoL improved significantly over the follow-up period. More contact with family and a better financial situation at baseline had a positive and longstanding effect on S-QoL-development, but changes in these variables were not associated with S-QoL-development. Higher depressive symptoms and less daily activities at baseline both had a negative independent effect, but a positive interaction effect with time on S-QoL-development indicating that the independent negative effect diminished over time. In the change analysis, increased daily activities and a decrease in depressive symptoms were associated with a positive S-QoL-development. Conclusions: Treatment of depressive symptoms and measures aimed at increasing daily activities seem important to improve S-QoL in patients with psychosis. More contact with family and a better financial situation at baseline have a long-standing effect on S-QoL-development in FEP patients.
AB - Subjective quality of life (S-QoL) is an important outcome measure in first episode psychosis (FEP). The aims of this study were to describe S-QoL-development the first 10-years in FEP patients and to identify predictors of this development. Methods: A representative sample of 272 patients with a first episode psychotic disorder was included from 1997 through 2000. At 10 year follow-up 186 patients participated. QoL was measured by the Lehman's Quality of Life Interview. Linear mixed model analyses were performed to investigate longitudinal effects of baseline psychiatric symptoms and socio-economic variables and the effects of changes in the same variables on S-QoL-development. Results: S-QoL improved significantly over the follow-up period. More contact with family and a better financial situation at baseline had a positive and longstanding effect on S-QoL-development, but changes in these variables were not associated with S-QoL-development. Higher depressive symptoms and less daily activities at baseline both had a negative independent effect, but a positive interaction effect with time on S-QoL-development indicating that the independent negative effect diminished over time. In the change analysis, increased daily activities and a decrease in depressive symptoms were associated with a positive S-QoL-development. Conclusions: Treatment of depressive symptoms and measures aimed at increasing daily activities seem important to improve S-QoL in patients with psychosis. More contact with family and a better financial situation at baseline have a long-standing effect on S-QoL-development in FEP patients.
KW - Journal Article
U2 - 10.1016/j.schres.2016.02.034
DO - 10.1016/j.schres.2016.02.034
M3 - Journal article
C2 - 26947210
SN - 0920-9964
VL - 172
SP - 23
EP - 28
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -